Myrotoxin B

Myrotoxin B
Identifiers

CAS Registry Number	99486-49-4^Y
Jmol-3D images	Image
PubChem	6540635
SMILES CC1=C[C@]2([H])[C@]([C@@](C)3[C@]4(CO4)[C@@]([H])(C[C@H]3OC5=O)O2)(CO[C@]([C@@H](O7)[C@]([C@H]/6O)7CCOC6=C/C/C=C\5)=O)C[C@@H]1OC(C)=O
Properties
Molecular formula	C₂₉H₃₄O₁₁
Molar mass	558.57 g·mol⁻¹
Melting point	195 to 197 °C (383 to 387 °F; 468 to 470 K)^[1]
Except where noted otherwise, data is given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
Y verify (what is: Y/N?)
Infobox references

Myrotoxin B is a macrocyclic trichothecene first isolated in 1985.^[1] It was tested on Swiss mice and found to be very toxic, though not the most toxic of the three toxins that were tested at that time.^[2] It has also been isolated from Myrothecium roridum, a pathogen leaf spot that affects mulberry, though it is unknown if it is used as a pathotoxin.^[3]

References

↑ 1.0 1.1 Jarvis, B. B.; Lee, Y.-W.; Cömezoḡlu, F. T.; Cömezoḡlu, S. N.; Bean, G. A. (1985). "Myrotoxins: a new class of macrocyclic trichothecenes". Tetrahedron Letters 26 (40): 4859–62. doi:10.1016/S0040-4039(00)94970-0.
↑ Schiefer, H. B.; Hancock, D. S.; Jarvis, B. B. (1989). "Toxicology of Novel Macrocyclic Trichothecenes, Baccharinoid B4, Myrotoxin B, and Roritoxin B". Zentralblatt für Veterinärmedizin. Reihe A 36 (2): 152–60. ISSN 0514-7158. PMID 2501953.
↑ Murakami, R.; Shirata, A. (2005). "Myrotoxin B Detection from Mulberry Leaves Infected with Myrothecium roridum, cause Myrothecium Leaf Spot of Mulberry, and Possible Roles in Pathogenicity" (PDF). Japanese Journal of Phytopathology 71 (2): 91–100. doi:10.3186/jjphytopath.71.91.