Mucosal associated invariant T cell

Mucosal associated invariant T cells (MAITs) are a special type of T cell, which have a canonical T cell receptor (Vα19-Jα33 in mice and Vα7.2-Jα33 in humans), and which appear to play a regulatory role in immunity.[1] They are dependent on gut microbiota, being absent in germ-free mice.[1]

References

  1. ↑ 1.0 1.1 "The Role of NKT Cells in Tumor Immunity". Adv Cancer Res 101: 277–348. 2008. doi:10.1016/S0065-230X(08)00408-9. PMC 2693255. PMID 19055947. Retrieved 8 March 2013.