Mother lode (disambiguation)
Mother lode may refer to:
- Mother lode, a principal vein or zone of veins of gold or silver ore
- Motherlode (band), a Canadian pop rock group formed in 1969
- Mother Lode (film), a 1982 adventure film directed by and starring Charlton Heston
- Motherlode (Loggins and Messina album), a 1974 album by Loggins and Messina
- Motherlode (James Brown album), a 1988 compilation album by James Brown
- Motherlode (Sara Hickman album), a 2006 album by Sara Hickman
- Motherlode climbing area in Red River Gorge, significant climbing area in Kentucky, well known for high concentration of high difficulty routes.