Morin (flavonol)
Morin
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Names |
IUPAC name
2-(2,4-dihydroxyphenyl)-3,5,7-trihydroxychromen-4-one |
Other names
Aurantica Al-Morin Morin hydrate Calico Yellow Toxylon pomiferum Bois d'arc Osage orange extract |
Identifiers |
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654055-01-3 |
ChEBI |
CHEBI:75092 |
ChEMBL |
ChEMBL28626 Y |
ChemSpider |
4444989 Y |
InChI=1S/C15H10O7/c16-6-1-2-8(9(18)3-6)15-14(21)13(20)12-10(19)4-7(17)5-11(12)22-15/h1-5,16-19,21H YKey: YXOLAZRVSSWPPT-UHFFFAOYSA-N YInChI=1/C15H10O7/c16-6-1-2-8(9(18)3-6)15-14(21)13(20)12-10(19)4-7(17)5-11(12)22-15/h1-5,16-19,21H Key: YXOLAZRVSSWPPT-UHFFFAOYAH
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IUPHAR ligand |
411 |
Jmol-3D images |
Image |
KEGG |
C10105 Y |
PubChem |
5281670 |
O=C1c3c(O/C(=C1/O)c2ccc(O)cc2O)cc(O)cc3O
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Properties |
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C15H10O7 |
Molar mass |
302.2357 g/mol |
Density |
1.799 g/mL |
Except where noted otherwise, data is given for materials in their standard state (at 25 °C (77 °F), 100 kPa) |
Y verify (what is: Y/N?) |
Infobox references |
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Morin is a chemical compound. It is a yellow color substance that can be isolated from Maclura pomifera (Osage orange), Maclura tinctoria (old fustic) and from leaves of Psidium guajava (common guava).[1] In a preclinical study it was found to be the most potent flavonoid inhibitor of fatty acid synthase tested with an IC50 of 2.33±0.09μM.[2]
Morin can be used to test for the presence of aluminium or tin in a solution, since it forms characteristically fluorescent coordination complexes with them.
Glycosides
- Morin-3-O-arabinoside[1]
- Morin-3-O-lyxoside[1]
References
- ↑ 1.0 1.1 1.2 Bacteriostatic effect of flavonoids isolated from leaves of Psidium guajava on fish pathogens. Rattanachaikunsopon Pongsak and Phumkhachorn Parichat,
INIST:19087798
- ↑ Tian, WX (February 2006). "Inhibition of Fatty Acid Synthase by Polyphenols". Current Medicinal Chemistry 13 (8): 967–977. doi:10.2174/092986706776361012. PMID 16611078.
Flavonols and their conjugates |
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| Backbone | |
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| Flavonols | Aglycones | |
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| Conjugates | | |
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- Afzelin (Kaempferol 3-rhamnoside)
- Astragalin (kaempferol 3-O-glucoside)
- Kaempferitrin (kaempferol 3,7-dirhamnoside)
- Juglanin (Kaempferol 3-O-arabinoside)
- Kaempferol 3-alpha-L-arabinopyranoside
- Kaempferol 3-alpha-D-arabinopyranoside
- Kaempferol 7-alpha-L-arabinoside
- Kaempferol 7-O-glucoside
- Kaempferol 3-lathyroside
- Kaempferol 4'-rhamnoside
- Kaempferol 5-rhamnoside
- Kaempferol 7-rhamnoside
- Kaempferol 7-O-alpha-L-rhamnofuranoside
- Kaempferol 3-xyloside
- Kaempferol 7-xyloside
- Robinin (kaempferol-3-O-robinoside-7-O-rhamnoside)
- Kaempferol 3-O-rutinoside
- Sophoraflavonoloside (Kaempferol 3-O-sophoroside)
- Trifolin (Kaempferol 3-O-beta-D-galactoside)
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| O-Methylated flavonols | Aglycones | |
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| Glycosides | of isorhamnetin |
- Narcissin (Isorhamnetin 3-O-rutinoside)
- Isorhamnetin 3-O-glucoside
- Tamarixetin 7-rutinoside
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| other |
- Azalein (Azaleatin 3-O-α-L-rhamnoside)
- Centaurein (Centaureidin 7-O-glucoside)
- Eupalin (Eupalitin 3-0-rhamnoside)
- Eupatolin (Eupatolitin 3-O-rhamnoside)
- Jacein (Jaceidin 7-O-glucoside)
- Patulitrin (Patuletin 7-O-glucoside
- Xanthorhamnin (Rhamnetin glycoside)
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| Derivative flavonols | Aglycones |
- Noricaritin
- Dihydronoricaritin
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| Glycosides | |
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| Pyranoflavonols | |
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| Furanoflavonols | |
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| Semisynthetic | |
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