Monoiodotyrosine

Monoiodotyrosine
Names
IUPAC name
N-Iodo-L-tyrosine
Identifiers
29592-76-5 Yes
ChemSpider 2297729 
Jmol-3D images Image
MeSH Monoiodotyrosine
PubChem 3032857
Properties
C9H10INO3
Molar mass 307.085 g/mol
Except where noted otherwise, data is given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
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Infobox references

Monoiodotyrosine is a precursor of thyroid hormone and results from iodization of tyrosine at the meta- position of the phenol ring.

Two units can combine to form 3,3'-diiodothyronine. One unit can combine with diiodotyrosine to form triiodothyronine, as occurs in the colloid of the thyroid follicle.

It is abbreviated "MIT".[1]

References

  1. Tietze F, Kohn LD, Kohn AD et al. (March 1989). "Carrier-mediated transport of monoiodotyrosine out of thyroid cell lysosomes". J. Biol. Chem. 264 (9): 4762–5. PMID 2925666.