Molybdopterin adenylyltransferase
| Molybdopterin adenylyltransferase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 2.7.7.75 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
Molybdopterin adenylyltransferase (EC 2.7.7.75, MogA, Cnx1) is an enzyme with system name ATP:molybdopterin adenylyltransferase.[1][2][3] This enzyme catalyses the following chemical reaction
- ATP + molybdopterin
diphosphate + adenylyl-molybdopterin
This enzyme catalyses the activation of molybdopterin for molybdenum insertion.
References
- ↑ Nichols, J.D. and Rajagopalan, K.V. (2005). "In vitro molybdenum ligation to molybdopterin using purified components". J. Biol. Chem. 280 (9): 7817–7822. doi:10.1074/jbc.M413783200. PMID 15632135.
- ↑ Kuper, J., Palmer, T., Mendel, R.R. and Schwarz, G. (2000). "Mutations in the molybdenum cofactor biosynthetic protein Cnx1G from Arabidopsis thaliana define functions for molybdopterin binding, molybdenum insertion, and molybdenum cofactor stabilization". Proc. Natl. Acad. Sci. USA 97 (12): 6475–6480. doi:10.1073/pnas.110568497. PMC 18627. PMID 10823911.
- ↑ Llamas, A., Mendel, R.R. and Schwarz, G. (2004). "Synthesis of adenylated molybdopterin: an essential step for molybdenum insertion". J. Biol. Chem. 279 (53): 55241–55246. doi:10.1074/jbc.M409862200. PMID 15504727.
External links
- Molybdopterin adenylyltransferase at the US National Library of Medicine Medical Subject Headings (MeSH)