MiRBase
 | |
|---|---|
| Content | |
| Description | microRNA annotation and deep-sequencing data. |
| Contact | |
| Research center | University of Manchester |
| Laboratory | Faculty of Life Sciences |
| Authors | Ana Kozomara |
| Primary citation | Kozomara & al. (2011)[1] |
| Release date | 2010 |
| Access | |
| Website | http://www.mirbase.org/ |
| Tools | |
| Miscellaneous | |
In bioinformatics, miRBase is a biological database that acts as an archive of microRNA sequences and annotations.[1][2][3][4] As of September 2010 it contained information about 15,172 microRNAs.[1] The miRBase registry provides a centralised system for assigning new names to microRNA genes.[5]
miRBase grew from the microRNA registry resource set up by Sam Griffiths-Jones in 2003.[6]
According to Kozomara and Griffiths-Jones miRBase has five aims:[1]
- To provide a consistent naming system for microRNAs
- To provide a central place collecting all known microRNA sequences
- To provide human and computer readable information for each microRNA
- To provide primary evidence for each microRNA
- To aggregate and link to microRNA target information
References
- ↑ 1.0 1.1 1.2 1.3 Kozomara, A.; Griffiths-Jones, S. (2010). "MiRBase: integrating microRNA annotation and deep-sequencing data". Nucleic Acids Research 39 (Database issue): D152–7. doi:10.1093/nar/gkq1027. PMC 3013655. PMID 21037258.
- ↑ Griffiths-Jones, Sam (2010). "MiRBase: microRNA Sequences and Annotation". pp. Unit 12.9.1–10. doi:10.1002/0471250953.bi1209s29.
- ↑ Griffiths-Jones, S.; Saini, H. K.; Van Dongen, S.; Enright, A. J. (2007). "MiRBase: tools for microRNA genomics". Nucleic Acids Research 36 (Database issue): D154–8. doi:10.1093/nar/gkm952. PMC 2238936. PMID 17991681.
- ↑ Griffiths-Jones, Sam (2006). "MiRBase: the MicroRNA Sequence Database" 342. pp. 129–38. doi:10.1385/1-59745-123-1:129.
- ↑ Griffiths-Jones, S.; Grocock, RJ; Van Dongen, S; Bateman, A; Enright, AJ (2006). "MiRBase: microRNA sequences, targets and gene nomenclature". Nucleic Acids Research 34 (Database issue): D140–4. doi:10.1093/nar/gkj112. PMC 1347474. PMID 16381832.
- ↑ Griffiths-Jones S (January 2004). "The microRNA Registry". Nucleic Acids Res. 32 (Database issue): D109–11. doi:10.1093/nar/gkh023. PMC 308757. PMID 14681370.