Metisazone

Metisazone

Names
IUPAC name [(1-Methyl-2-oxoindol-3-ylidene)amino]thiourea
Other names Metisazone
Identifiers
ATC code	J05AA01
CAS Registry Number	1910-68-5 Y
ChEMBL	ChEMBL1512080 N
ChemSpider	5259074
EC number	217-616-2
InChI InChI=1S/C10H10N4OS/c1-14-7-5-3-2-4-6(7)8(9(14)15)12-13-10(11)16/h2-5H,1H3,(H3,11,13,16)/b12-8- Key: DLGSOJOOYHWROO-WQLSENKSSA-N InChI=1/C10H10N4OS/c1-14-7-5-3-2-4-6(7)8(9(14)15)12-13-10(11)16/h2-5H,1H3,(H3,11,13,16)/b12-8- Key: DLGSOJOOYHWROO-WQLSENKSBL
Jmol-3D images	Image
KEGG	D02496
MeSH	D008720
PubChem	6861563
SMILES CN1C2=CC=CC=C2C(=NNC(=S)N)C1=O
UNII	K3QML4J07E N
Properties
Chemical formula	C10H10N4OS
Molar mass	234.28 g/mol
Except where noted otherwise, data is given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
N verify (what is: Y/N?)
Infobox references

Methisazone (USAN) or metisazone (INN) is an antiviral drug that works by inhibiting mRNA and protein synthesis, especially in pox viruses. It has been used in the past to treat smallpox.^[1]

Methisazone has been described as being used in prophylaxis since at least 1965.^[2][3]

References