Mephenoxalone

Mephenoxalone
Systematic (IUPAC) name

5-[(2-methoxyphenoxy)methyl]-1,3-oxazolidin-2-one
Clinical data
Trade names	Dorsiflex, Moderamin, Control-OM
AHFS/Drugs.com	International Drug Names
Identifiers
CAS Registry Number	70-07-5^Y
ATC code	N05BX01
PubChem	CID 6257
ChemSpider	6021^N
UNII	CZ87T54W8W^Y
KEGG	D07318^Y
ChEMBL	CHEMBL2104790^N
Chemical data
Formula	C₁₁H₁₃N O₄
Molecular mass	223.225 g/mol
SMILES O=C2OC(COc1c(OC)cccc1)CN2
InChI InChI=1S/C11H13NO4/c1-14-9-4-2-3-5-10(9)15-7-8-6-12-11(13)16-8/h2-5,8H,6-7H2,1H3,(H,12,13) ^N Key:ZMNSRFNUONFLSP-UHFFFAOYSA-N ^N
N (what is this?) (verify)

Mephenoxalone (trade names Dorsiflex, Moderamin, Control-OM) is a muscle relaxant^[1] and mild anxiolytic.^[2] It inhibits neuron transmission, relaxing skeletal muscles by inhibiting the reflex arc. As the effect of muscle relaxation, mephenoxalone affects mental condition, and is also a treatment for nervousness and anxiety.

References

↑ Magnenat, M. (1961). "The utilization in psychotherapy of a tensiolytic agent with muscle relaxant effect, Control OM (mephenoxalone), alone or associated with thymoleptics". Therapeutische Umschau. Revue therapeutique 18: 516–520. PMID 14468333.
↑ MIMS: Mephenoxalone

GABA_AR PAMs

Others

^#WHO-EM
^‡Withdrawn from market
Clinical trials:
- ^†Phase III
- ^§Never to phase III

Index of psychology and psychiatry

Description	Mental processes

Disorders	Mental and behavioral ADHD OCD Tourette's Mood Developmental pervasive dyslexia and specific Substance-related alcohol Emotional and behavioral Symptoms and signs eponymous Evaluation and testing

Treatment	Psychotherapy CBT Drugs depression antipsychotics anxiety dementia hypnotics and sedatives psychostimulants, ADHD and nootropics

Skeletal muscle relaxants (M03)

Peripherally acting
(primarily antinicotinic,
NMJ block)

Non-depolarizing

Curare alkaloids	Alcuronium Dimethyltubocurarine Tubocurarine

4° ammonium agents	ultra-short duration: Gantacurium short duration: Mivacurium Chandonium intermediate duration: Atracurium Cisatracurium Fazadinium Rocuronium Vecuronium long duration: Doxacurium Dimethyltubocurarine Pancuronium Pipecuronium Laudexium Gallamine unsorted: Hexafluronium (Hexafluorenium)

Depolarizing

Choline derivatives: Suxamethonium (Succinylcholine)

Polyalkylene derivatives: Hexamethonium

ACh release inhibitors

Botulinum toxin

Centrally acting

Carbamic acid esters	Carisoprodol Cyclarbamate Difebarbamate Febarbamate Meprobamate Methocarbamol Phenprobamate Styramate Tybamate

Benzodiazepines	Bromazepam Diazepam Clonazepam Flunitrazepam Lorazepam Nitrazepam Temazepam Tetrazepam

Nonbenzodiazepines	Eszopiclone

Thienodiazepines	Etizolam

Quinazolines	Methaqualone

Anticholinergics (Antimuscarinics)	Cyclobenzaprine Orphenadrine

Other	Arbaclofen placarbil Baclofen Chlormezanone Chlorphenesin Chlorzoxazone Donepezil Eperisone Fenyramidol Flopropione Gabapentin GHB Mephenesin Mephenoxalone Metaxalone Phenibut Pregabalin Pridinol Promoxolane Quinine Thiocolchicoside Tizanidine Tolperisone

Directly acting

Dantrolene

Index of muscle

Description	Anatomy head neck arms chest and back diaphragm abdomen genital area legs Muscle tissue Physiology connective tissue

Disease	Myopathy Soft tissue Connective tissue Congenital abdomen muscular dystrophy Neoplasms and cancer Injury Symptoms and signs eponymous

Treatment	Procedures Drugs anti-inflammatory muscle relaxants