Menogaril

Menogaril

Names
Other names 7-O-Methylnogarol
Identifiers
CAS Registry Number	71628-96-1 Y
ChEMBL	ChEMBL1234391 N
ChemSpider	4450900 N
InChI InChI=1S/C28H31NO10/c1-27(36)8-10-6-11-16(21(32)15(10)14(9-27)37-5)22(33)17-13(30)7-12-24(18(17)20(11)31)38-26-23(34)19(29(3)4)25(35)28(12,2)39-26/h6-7,14,19,23,25-26,30,32,34-36H,8-9H2,1-5H3/t14-,19+,23+,25-,26-,27-,28-/m1/s1 N Key: LWYJUZBXGAFFLP-OCNCTQISSA-N N InChI=1/C28H31NO10/c1-27(36)8-10-6-11-16(21(32)15(10)14(9-27)37-5)22(33)17-13(30)7-12-24(18(17)20(11)31)38-26-23(34)19(29(3)4)25(35)28(12,2)39-26/h6-7,14,19,23,25-26,30,32,34-36H,8-9H2,1-5H3/t14-,19+,23+,25-,26-,27-,28-/m1/s1 Key: LWYJUZBXGAFFLP-OCNCTQISBR
Jmol-3D images	Image
PubChem	5288818
SMILES C[C@@]1(C[C@H](C2=C(C3=C(C=C2C1)C(=O)C4=C5C(=CC(=C4C3=O)O)[C@@]6([C@@H]([C@H]([C@@H]([C@H](O5)O6)O)N(C)C)O)C)O)OC)O
UNII	8JSV4O30HQ N
Properties
Chemical formula	C28H31NO10
Molar mass	541.55 g/mol
Except where noted otherwise, data is given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
N verify (what is: Y/N?)
Infobox references

Menogaril is an anthracycline analog of nogalamycin which was developed in late 1970s. It has even stronger anticancer activity than nogalamycin and has less toxicity than nogalamycin. However, its development for clinical use was cancelled.^[1]

References

1. ↑ Moore DF Jr, Brown TD, LeBlanc M, Dahlberg S, Miller TP, McClure S, Fisher RI. (1999). "Phase II trial of menogaril in non-Hodgkin's lymphomas: a Southwest Oncology Group trial.". Invest New Drugs. 17 (2): 169–72. doi:10.1023/A:1006375301205.