Mebroqualone

Mebroqualone

Systematic (IUPAC) name
3-(2-bromophenyl)-2-methylquinazolin-4(3H)-one
Clinical data
Identifiers
ATC code	None
PubChem	CID 364842
ChemSpider	323878 Y
Chemical data
Formula	C15H11BrN2O
SMILES BrC1=C(N2C(C3=CC=CC=C3N=C2C)=O)C=CC=C1
InChI InChI=1S/C15H11BrN2O/c1-10-17-13-8-4-2-6-11(13)15(19)18(10)14-9-5-3-7-12(14)16/h2-9H,1H3  Y Key:NBUSAPJNASSKBP-UHFFFAOYSA-N  Y
Y (what is this?)  (verify)

Mebroqualone (MBQ) is a quinazolinone-class GABAergic and is an analogue of mecloqualone that has similar sedative and hypnotic properties to its parent compound, resulting from its agonist activity at the β subtype of the GABA_a receptor. It was originally synthesized in the 1960s^[1] Mebroqualone differs from mecloqualone by having a bromine atom instead of a chlorine on the 3-phenyl ring. It was made illegal in Germany in 1998 but little other information is available. It would appear that this compound was sold on the black market in Germany as a designer drug analogue of mecloqualone.^[2]

See also

• Methaqualone
• Afloqualone
• Etaqualone
• Methylmethaqualone
• Mecloqualone
• Cloroqualone
• Diproqualone
• Gamma-Aminobutyric acid

References

1. ↑ Jackman et al. Journal of Pharmacy and Pharmacology, 1960 , vol. 12, p. 529
2. ↑ Zwölfte Verordnung zur Änderung betäubungsmittelrechtlicher Vorschriften. Bundesgesetzblatt 1998: Part I Number 68, p. 3126. 7 October 1998.