Malotilate
Systematic (IUPAC) name | |
---|---|
diisopropyl 1,3-dithiol-2-ylidenemalonate | |
Clinical data | |
AHFS/Drugs.com | International Drug Names |
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Oral | |
Identifiers | |
59937-28-9 | |
None | |
PubChem | CID 4006 |
ChemSpider | 3866 |
UNII | RV59PND975 |
ChEMBL | CHEMBL1697754 |
Chemical data | |
Formula | C12H16O4S2 |
288.38 g/mol | |
SMILES
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Malotilate (INN) is a drug used in the treatment of liver disease. It has been shown to facilitate liver regeneration in rats.[1]
References
- Bührer M, Le Cotonnec JY, Wermeille M, Bircher J (1986). "Treatment of liver disease with malotilate. A pharmacokinetic and pharmacodynamic phase II study in cirrhosis". Eur. J. Clin. Pharmacol. 30 (4): 407–16. doi:10.1007/BF00607952. PMID 3743616.
- Siegers CP, Pauli V, Korb G, Younes M (August 1986). "Hepatoprotection by malotilate against carbon tetrachloride-alcohol-induced liver fibrosis". Agents Actions 18 (5–6): 600–3. doi:10.1007/BF01964970. PMID 3766314.
- Younes M, Siegers CP (May 1985). "Effect of malotilate on paracetamol-induced hepatotoxicity". Toxicol. Lett. 25 (2): 143–6. doi:10.1016/0378-4274(85)90074-8. PMID 4002245.