MYO1E

Myosin IE

Identifiers

MYO1E ; FSGS6; HuncM-IC; MYO1C

External IDs

OMIM: 601479 MGI: 106621 HomoloGene: 55864 GeneCards: MYO1E Gene

Gene ontology
Molecular function	• microfilament motor activity • motor activity • protein binding • calmodulin binding • ATP binding • phosphatidylinositol binding • ATPase activity, coupled • actin filament binding
Cellular component	• cytoplasm • cytoskeleton • cell-cell junction • adherens junction • actin cytoskeleton • myosin complex • clathrin-coated endocytic vesicle • extracellular vesicular exosome
Biological process	• vasculogenesis • in utero embryonic development • glomerular filtration • ATP catabolic process • endocytosis • actin filament-based movement • glomerular basement membrane development • post-embryonic hemopoiesis • platelet-derived growth factor receptor signaling pathway • glomerular visceral epithelial cell development
Sources: Amigo / QuickGO

RNA expression pattern

More reference expression data

Orthologs

Species

Human

Mouse

ENSG00000157483

ENSMUSG00000032220

RefSeq (mRNA)

RefSeq (protein)

Location (UCSC)

Chr 15:
59.43 – 59.67 Mb

Chr 9:
70.21 – 70.4 Mb

PubMed search

Myosin-Ie is a protein that in humans is encoded by the MYO1E gene.^[1]^[2]

References

↑ Hasson T, Skowron JF, Gilbert DJ, Avraham KB, Perry WL, Bement WM, Anderson BL, Sherr EH, Chen ZY, Greene LA, Ward DC, Corey DP, Mooseker MS, Copeland NG, Jenkins NA (Feb 1997). "Mapping of unconventional myosins in mouse and human". Genomics 36 (3): 431–9. doi:10.1006/geno.1996.0488. PMID 8884266.
↑ "Entrez Gene: MYO1E myosin IE".

Further reading

Krendel M, Osterweil EK, Mooseker MS (2007). "Myosin 1E interacts with synaptojanin-1 and dynamin and is involved in endocytosis.". FEBS Lett. 581 (4): 644–50. doi:10.1016/j.febslet.2007.01.021. PMC 1861834. PMID 17257598.
Strausberg RL; Feingold EA; Grouse LH et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
El Mezgueldi M, Tang N, Rosenfeld SS, Ostap EM (2002). "The kinetic mechanism of Myo1e (human myosin-IC)". J. Biol. Chem. 277 (24): 21514–21. doi:10.1074/jbc.M200713200. PMID 11940582.
Skowron JF, Bement WM, Mooseker MS (1999). "Human brush border myosin-I and myosin-Ic expression in human intestine and Caco-2BBe cells". Cell Motil. Cytoskeleton 41 (4): 308–24. doi:10.1002/(SICI)1097-0169(1998)41:4<308::AID-CM4>3.0.CO;2-J. PMID 9858156.
Robertson H, Langdon WY, Thien CB, Bowtell DD (1997). "A c-Cbl yeast two hybrid screen reveals interactions with 14-3-3 isoforms and cytoskeletal components". Biochem. Biophys. Res. Commun. 240 (1): 46–50. doi:10.1006/bbrc.1997.7608. PMID 9367879.
Bement WM; Hasson T; Wirth JA et al. (1994). "Identification and overlapping expression of multiple unconventional myosin genes in vertebrate cell types". Proc. Natl. Acad. Sci. U.S.A. 91 (14): 6549–53. doi:10.1073/pnas.91.14.6549. PMC 44240. PMID 8022818.
Bement WM, Wirth JA, Mooseker MS (1994). "Cloning and mRNA expression of human unconventional myosin-IC. A homologue of amoeboid myosins-I with a single IQ motif and an SH3 domain". J. Mol. Biol. 243 (2): 356–63. doi:10.1006/jmbi.1994.1662. PMID 7932763.