MPHOSPH8

M-phase phosphoprotein 8

Available structures

Ortholog search: PDBe, RCSB

List of PDB id codes
3LWE, 3QO2, 3R93, 3SVM

Identifiers

MPHOSPH8 ; HSMPP8; TWA3; mpp8

External IDs

OMIM: 611626 MGI: 1922589 HomoloGene: 11380 ChEMBL: 1741210 GeneCards: MPHOSPH8 Gene

Gene ontology
Molecular function	• protein binding • methylated histone binding
Cellular component	• nuclear nucleosome • nucleus • nuclear heterochromatin • nucleolus • cytoplasm • plasma membrane • extracellular vesicular exosome
Biological process	• transcription, DNA-templated • cell cycle • regulation of DNA methylation • negative regulation of transcription, DNA-templated
Sources: Amigo / QuickGO

RNA expression pattern

More reference expression data

Orthologs

Species

Human

Mouse

ENSG00000255836

ENSMUSG00000079184

RefSeq (mRNA)

RefSeq (protein)

Location (UCSC)

Chr 12:
7.59 – 7.59 Mb

Chr 14:
56.67 – 56.7 Mb

PubMed search

M-phase phosphoprotein 8 is an enzyme that in humans is encoded by the MPHOSPH8 gene.^[1]^[2]

References

↑ Matsumoto-Taniura N, Pirollet F, Monroe R, Gerace L, Westendorf JM (Jan 1997). "Identification of novel M phase phosphoproteins by expression cloning". Mol Biol Cell 7 (9): 1455–69. doi:10.1091/mbc.7.9.1455. PMC 275994. PMID 8885239.
↑ "Entrez Gene: HSMPP8 M-phase phosphoprotein, mpp8".

Further reading

Olsen JV, Blagoev B, Gnad F et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.". Cell 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.
Maksimov VV, Arman IP, Tarantul VZ (2006). "[Identification of the proteins interacting with neuroprotective peptide humanin in a yeast two-hybrid system]". Genetika 42 (2): 274–7. PMID 16583711.
Gerhard DS, Wagner L, Feingold EA et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Dunham A, Matthews LH, Burton J et al. (2004). "The DNA sequence and analysis of human chromosome 13.". Nature 428 (6982): 522–8. doi:10.1038/nature02379. PMC 2665288. PMID 15057823.
Ota T, Suzuki Y, Nishikawa T et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Umeda M, Nishitani H, Nishimoto T (2003). "A novel nuclear protein, Twa1, and Muskelin comprise a complex with RanBPM.". Gene 303: 47–54. doi:10.1016/S0378-1119(02)01153-8. PMID 12559565.
Strausberg RL, Feingold EA, Grouse LH et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.