Lutheran antigen system

Lutheran antigen system is a human blood group system based upon the LU protein from the BCAM gene, also called CD239, on chromosome 19.

This system is a single locus system, with antigens Lua and Lub. The Lu(b) negative phenotype is very rare. Antibodies to Lutheran antigens are IgG. The genes of the Lutheran group are linked to the genes responsible for the secretion of ABH substances.

A complex blood group system having pairs of alternate antigens and amorphic genes, but also subject to a dominant independently segregating repressor.

External links

Lutheran at BGMUT Blood Group Antigen Gene Mutation Database at NCBI, NIH

Transfusion medicine

General concepts

Apheresis (plasmapheresis, plateletpheresis, leukapheresis)
Blood transfusion
Coombs test (direct and indirect)
Cross-matching
Exchange transfusion
International Society of Blood Transfusion
Intraoperative blood salvage
ISBT 128
Transfusion reactions

Blood group systems /
blood types

Blood products /
blood donation

Whole blood
Platelets
Red blood cells
Plasma / Fresh frozen plasma / PF24 (Cryoprecipitate + Cryosupernatant)
Blood substitutes

Index of cells from bone marrow

Description	Immune system Cells Physiology coagulation proteins granule contents colony-stimulating heme and porphyrin metabolism intermediates

Disease	Red blood cell Monocyte and granulocyte Neoplasms and cancer Histiocytosis Symptoms and signs eponymous Blood tests findings

Treatment	Transfusion Drugs thrombosis bleeding other