Lurtotecan
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Identifiers | |
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149882-10-0 ![]() | |
ChEMBL | ChEMBL305666 ![]() |
ChemSpider | 54919 ![]() |
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Jmol-3D images | Image |
PubChem | 60956 |
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Properties | |
C28H30N4O6 | |
Molar mass | 518.561 g/mol |
Except where noted otherwise, data is given for materials in their standard state (at 25 °C (77 °F), 100 kPa) | |
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Infobox references | |
Lurtotecan is an analogue of camptothecin.
Synthesis
![](../I/m/Lurtotecan_synthesis.png)
Lurtotecan synthesis:[1]
- Potassium osmate
- Sharpless asymmetric dihydroxylation
- Heck reaction
- Swern oxidation
- Mitsunobu reaction
References
- ↑ Fang, F. G.; Bankston, D. D.; Huie, E. M.; Ross Johnson, M.; Kang, M. C.; Lehoullier, C. S.; Lewis, G. C.; Lovelace, T. C.; Lowery, M. W.; McDougald, D. L.; Meerholz, C. A.; Partridge, J. J.; Sharp, M. J.; Xie, S. (1997). "Convergent catalytic asymmetric synthesis of camptothecin analog GI147211C". Tetrahedron 53 (32): 10953. doi:10.1016/S0040-4020(97)00357-8.