List of IARC Group 2A carcinogens

The agents in this list have been classified in Group 2A (probable carcinogens)^[1] by the IARC (International Agency for Research on Cancer). The term "agent" encompasses both substances and exposure circumstances that pose a risk. This designation is applied when there is limited evidence of carcinogenicity in humans as well as sufficient evidence of carcinogenicity in experimental animals. In some cases, an agent may be classified in this group when there is inadequate evidence of carcinogenicity in humans along with sufficient evidence of carcinogenicity in experimental animals and strong evidence that the carcinogenesis is mediated by a mechanism that also operates in humans. Exceptionally, an agent may be classified in this group solely on the basis of limited evidence of carcinogenicity in humans.

Agents

Substances

• Acrylamide
• Adriamycin
• Androgenic (anabolic) steroids
• Azacitidine
• Benz[a]anthracene
• BCNU (Bischloroethyl nitrosourea)
• Captafol
• Chloramphenicol
• α-Chlorinated toluenes (benzal chloride, benzotrichloride, benzyl chloride) and benzoyl chloride (combined exposures)
• CCNU (1-(2-Chloroethyl)-3-cyclohexyl-1-nitrosourea)
• 4-Chloro-ortho-toluidine
• Chlorozotocin
• Cisplatin
• Cyclopenta[cd]pyrene
• Clonorchis sinensis (infection with)
• Diazinon
• Dibenz[a,h]anthracene
• Dibenzo[a,l]pyrene
• Diethyl sulfate
• Dimethylcarbamoyl chloride
• 1,2-Dimethylhydrazine
• Dimethyl sulfate
• Epichlorohydrin
• Ethylene dibromide
• Ethyl carbamate (urethane)
• N-Ethyl-N-nitrosourea
• Etoposide
• Glycidol
• Glyphosate
• Indium phosphide
• 2-Amino-3-methylimidazo[4,5-f]quinoline (IQ)
• Lead compounds, inorganic
• Kaposi's sarcoma herpesvirus/human herpesvirus 8
• Malathion
• 5-Methoxypsoralen
• Methyl methanesulfonate
• MNNG (N-Methyl-N'-nitro-N-nitrosoguanidine)
• N-Methyl-N-nitrosourea
• Nitrate or nitrite (ingested) under conditions that result in endogenous nitrosation
• Nitrogen mustard
• N-Nitrosodiethylamine (DEN)
• N-Nitrosodimethylamine (NDMA)
• Phenacetin
• Procarbazine hydrochloride
• Styrene-7,8-oxide
• Teniposide
• Tetrachloroethylene
• Trichloroethylene
• 1,2,3-Trichloropropane
• Tris(2,3-dibromopropyl) phosphate
• Ultraviolet radiation A
• Ultraviolet radiation B
• Ultraviolet radiation C
• Vinyl bromide
• Vinyl fluoride

Mixtures

• Creosotes (from coal tars)
• High-temperature frying, emissions from
• Hot mate
• Household combustion of biomass fuel (primarily wood), indoor emissions from
• Non-arsenical insecticides (occupational exposures in spraying and application of)

Exposure circumstances

• Art glass, glass containers and pressed ware (manufacture of)
• Carbon electrode manufacture
• Cobalt metal with tungsten carbide
• Hairdresser or barber (occupational exposure as a)
• Petroleum refining (occupational exposures in)
• Shift work that involves circadian disruption

References

1. ↑ "Classifications" page on the IARC Monographs website

External links

• IARC Monographs - Classifications - Group2A