Levodropropizine
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| Systematic (IUPAC) name | |
|---|---|
| (2S)-3-(4-phenylpiperazin-1-yl)propane-1,2-diol | |
| Clinical data | |
| AHFS/Drugs.com | International Drug Names |
| Pharmacokinetic data | |
| Protein binding | 11-14% |
| Excretion | 83% via urine within 96 h |
| Identifiers | |
99291-25-5  | |
| R05DB27 | |
| PubChem | CID 65859 |
| ChemSpider |
59270 |
| UNII |
3O31P6T4G3 |
| KEGG |
D08119 |
| ChEBI |
CHEBI:82722  |
| Chemical data | |
| Formula | C13H20N2O2 |
| 236.31 g/mol | |
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Levodropropizine is a cough suppressant. It is the levo isomer of dropropizine. It acts as a peripheral antitussive, with no action in the central nervous system.[1] It does not cause side effects such as constipation or respiratory depression which can be produced by opioid antitussives such as codeine and its derivatives.
References
- ↑ De Blasio, F.; Dicpinigaitis, P. V.; Rubin, B. K.; De Danieli, G.; Lanata, L.; Zanasi, A. (2012). "An observational study on cough in children: Epidemiology, impact on quality of sleep and treatment outcome". Cough 8 (1): 1. doi:10.1186/1745-9974-8-1. PMC 3274450. PMID 22269875.
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