Lelis syndrome
Lelis syndrome |
---|
Classification and external resources |
---|
OMIM |
608290 |
---|
Lelis syndrome it is a genetic disorder, a rare condition with dermatological and dental findings[1] characterized by the association of ectodermal dysplasia (hypotrichosis and hypohidrosis) with acanthosis nigricans. Other clinical features may include palmoplantar hyperkeratosis, nail dystrophy, intellectual deficit,[2] disturbances of skin pigmentation (perioral and periorbital hyperpigmentation, vitiligo, and perinevic leukoderma)[2] and hypodontia. Transmission is autosomal recessive.[1][3]
See also
References
- ↑ 1.0 1.1 Samdani AJ (October 2004). "Ectodermal dysplasia with acanthosis nigricans (Lelis' syndrome)". J Coll Physicians Surg Pak 14 (10): 626–7. doi:10.2004/JCPSP.626627. PMID 15456556.
- ↑ 2.0 2.1 Lelis J (June 1992). "Autosomal recessive ectodermal dysplasia". Cutis 49 (6): 435–7. PMID 1628512.
- ↑ Steiner CE, Cintra ML, Marques-de-Faria AP (December 2002). "Ectodermal dysplasia with acanthosis nigricans (Lelis syndrome)". Am. J. Med. Genet. 113 (4): 381–4. doi:10.1002/ajmg.b.10787. PMID 12457412.
|
---|
| Genodermatosis | Congenital ichthyosis/ erythrokeratodermia | |
---|
| EB and related |
- EBS
- EBS-K
- EBS-WC
- EBS-DM
- EBS-OG
- EBS-MD
- EBS-MP
|
---|
| Ectodermal dysplasia | |
---|
| Elastic/Connective | |
---|
| Hyperkeratosis/ keratinopathy | PPK |
- diffuse: Diffuse epidermolytic palmoplantar keratoderma
- Diffuse nonepidermolytic palmoplantar keratoderma
- Palmoplantar keratoderma of Sybert
- Mal de Meleda
|
---|
| Other | |
---|
|
---|
| Other |
see also Template:Congenital malformations and deformations of skin appendages, Template:Phakomatoses, Template:Pigmentation disorders, Template:DNA replication and repair-deficiency disorder
|
---|
|
---|
| Developmental anomalies | Midline | |
---|
| Nevus | |
---|
| Other/ungrouped | |
---|
|
---|
| |
---|
| Description |
- Anatomy
- Physiology
- Development
|
---|
| Disease |
- Infections
- Vesiculobullous
- Dermatitis and eczema
- Papulosquamous
- Urticaria and erythema
- Radiation-related
- Pigmentation
- Mucinoses
- Keratosis, ulcer, atrophy, and necrobiosis
- Vasculitis
- Fat
- Neutrophilic and eosinophilic
- Congenital
- Neoplasms and cancer
- nevi and melanomas
- epidermis
- dermis
- Symptoms and signs
- Terminology
|
---|
| Treatment |
- Procedures
- Drugs
- antibiotics
- disinfectants
- emollients and protectives
- itch
- psoriasis
- other
- Wound and ulcer
|
---|
|
|