Leelamine

Leelamine

Names
IUPAC name [(1R,4aS,10aR)-1,4a-Dimethyl-7-propan-2-yl-2,3,4,9,10,10a-hexahydrophenanthren-1-yl]methanamine
Systematic IUPAC name Abieta-8,11,13-trien-18-amine
Other names (+)-Dehydroabietylamine; Amine D
Identifiers
CAS Registry Number	1446-61-3
ChemSpider	55878
InChI InChI=1S/C20H31N/c1-14(2)15-6-8-17-16(12-15)7-9-18-19(3,13-21)10-5-11-20(17,18)4/h6,8,12,14,18H,5,7,9-11,13,21H2,1-4H3/t18-,19-,20+/m0/s1 Key: JVVXZOOGOGPDRZ-SLFFLAALSA-N InChI=1/C20H31N/c1-14(2)15-6-8-17-16(12-15)7-9-18-19(3,13-21)10-5-11-20(17,18)4/h6,8,12,14,18H,5,7,9-11,13,21H2,1-4H3/t18-,19-,20+/m0/s1 Key: JVVXZOOGOGPDRZ-SLFFLAALBG
Jmol-3D images	Image
PubChem	62034
SMILES CC(C)c1ccc2c(c1)CC[C@@H]3[C@@]2(CCC[C@@]3(C)CN)C
Properties
Molecular formula	C20H31N
Molar mass	285.47 g·mol−1
Except where noted otherwise, data is given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
Infobox references

Leelamine (dehydroabietylamine) is a diterpene amine that has weak affinity for the cannabinoid receptors CB₁ and CB₂, as well as being an inhibitor of pyruvate dehydrogenase kinase.^[1] Optically active leelamine is also used as a chiral resolving agent for carboxylic acids.^[2][3]

See also

• THC
• Resin acid

References

1. ↑ "Leelamine - Dehydroabietylamine - Cayman Chemical". Retrieved May 20, 2013. 
2. ↑ US patent 3454626 
3. ↑ US patent 4559178