Laurence Hurst

Laurence D. Hurst
Institutions University of Bath, University of Oxford, University of Cambridge, Harvard University
Alma mater University of Oxford, University of Cambridge
Doctoral advisor W. D. Hamilton[1] and Alan Grafen[2]
Doctoral students Gilean McVean
Notable awards Scientific Medal of the Zoological Society of London (2003)[3]
Elected member of European Molecular Biology Organization (2004)[4]
The Genetics Society Medal (2010)[5]
FRS (2015)[6]

Laurence D. Hurst FRS is a Professor of Evolutionary Genetics in the Department of Biology and Biochemistry at The University of Bath.[7][8] Hurst completed his Bachelor of Arts in Zoology at Churchill College, Cambridge in 1987.[9] After a year at Harvard University he returned to the UK, obtaining a D.Phil at the University of Oxford in 1991 under the supervision of W. D. Hamilton and Alan Grafen. He was a Royal Society Research Fellow at the University of Cambridge from 1993 to 1996 and has been a Professor at the University of Bath since 1997.

His research[10] interests include evolution, genetics and genomics using computational and mathematical techniques to understand the way genes and genomes evolve. This has resulted in work on housekeeping genes,[11] gene orders[12][13] and the evolution of drug resistance in Staphylococcus aureus,[14] Saccharomyces cerevisiae [15][16][17] and the evolution of sexual reproduction / sexual dimorphism.[18]

References

  1. ↑ Hurst, L.; Hamilton, W.; Ladle, R. (1992). "Covert sex". Trends in Ecology & Evolution 7 (5): 144–145. doi:10.1016/0169-5347(92)90205-P. PMID 21235987.
  2. ↑ Hurst, L.; Grafen, A. (1990). "Sex and flagellation". Trends in Ecology & Evolution 5 (12): 419–422. doi:10.1016/0169-5347(90)90029-D. PMID 21232406.
  3. ↑ http://static.zsl.org/files/2010-scientific-1161.pdf Zoological Society of London Scientific Medal Winners
  4. ↑ http://www.embo.org/embo-members/find-a-member.html Find an EMBO member
  5. ↑ http://www.genetics.org.uk/page/2775/2010-Genetics-Society-Medal.html 2010 Genetics Society Medal
  6. ↑ https://royalsociety.org/people/fellowship/2015/laurence-hurst/
  7. ↑ http://www.bath.ac.uk/bio-sci/research/profiles/hurst-l.html Laurence Hurst at the University of Bath
  8. ↑ http://people.bath.ac.uk/bssldh/LaurenceDHurst/Home.html Hurst Laboratory of Evolutionary Genetics and Genomics
  9. ↑ http://people.bath.ac.uk/bssldh/LaurenceDHurst/CV.html Laurence Hurst CV
  10. ↑ http://scholar.google.com/scholar?q=laurence+hurst Laurence Hurst in Google Scholar
  11. ↑ Lercher, M.J.; Urrutia, A.O.; Hurst, L.D. (2002). "Clustering of housekeeping genes provides a unified model of gene order in the human genome". Nature Genetics 31 (2): 180–183. doi:10.1038/ng887. PMID 11992122.
  12. ↑ Hurst, L.D.; Pál, C.; Lercher, M.J. (2004). "The evolutionary dynamics of eukaryotic gene order". Nature Reviews Genetics 5 (4): 299–310. doi:10.1038/nrg1319. PMID 15131653.
  13. ↑ Weber, C. C.; Hurst, L. D. (2011). "Support for multiple classes of local expression clusters in Drosophila melanogaster, but no evidence for gene order conservation". Genome Biology 12 (3): R23. doi:10.1186/gb-2011-12-3-r23. PMC 3129673. PMID 21414197.
  14. ↑ Holden, M. T. G.; Feil, E.; Lindsay, J.; Peacock, S.; Day, N.; Enright, M.; Foster, T.; Moore, C.; Hurst, L.; Atkin, R.; Barron, A.; Bason, N.; Bentley, S. D.; Chillingworth, C.; Chillingworth, T.; Churcher, C.; Clark, L.; Corton, C.; Cronin, A.; Doggett, J.; Dowd, L.; Feltwell, T.; Hance, Z.; Harris, B.; Hauser, H.; Holroyd, S.; Jagels, K.; James, K. D.; Lennard, N.; Line, A. (2004). "Complete genomes of two clinical Staphylococcus aureus strains: Evidence for the rapid evolution of virulence and drug resistance". Proceedings of the National Academy of Sciences 101 (26): 9786–9791. doi:10.1073/pnas.0402521101. PMC 470752. PMID 15213324.
  15. ↑ Papp, B.Z.; Pál, C.; Hurst, L.D. (2003). "Dosage sensitivity and the evolution of gene families in yeast". Nature 424 (6945): 194–197. doi:10.1038/nature01771. PMID 12853957.
  16. ↑ Pál, C.; Papp, B.; Hurst, L. (2001). "Highly expressed genes in yeast evolve slowly". Genetics 158 (2): 927–931. PMC 1461684. PMID 11430355.
  17. ↑ Weber, C. C.; Hurst, L. D. (2009). "Protein Rates of Evolution Are Predicted by Double-Strand Break Events, Independent of Crossing-over Rates". Genome Biology and Evolution 1: 340–349. doi:10.1093/gbe/evp033. PMC 2817428. PMID 20333203.
  18. ↑ Hurst, L.; Peck, J. (1996). "Recent advances in understanding of the evolution and maintenance of sex". Trends in ecology & evolution 11 (2): 46–52. doi:10.1016/0169-5347(96)81041-X. PMID 21237760.