KRT36
| Keratin 36 | |||||||||||||
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| Identifiers | |||||||||||||
| Symbols | KRT36 ; HA6; KRTHA6; hHa6 | ||||||||||||
| External IDs | OMIM: 604540 HomoloGene: 88459 GeneCards: KRT36 Gene | ||||||||||||
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| RNA expression pattern | |||||||||||||
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| Orthologs | |||||||||||||
| Species | Human | Mouse | |||||||||||
| Entrez | 8689 | 16673 | |||||||||||
| Ensembl | ENSG00000126337 | ENSMUSG00000020916 | |||||||||||
| UniProt | O76013 | B1AQ75 | |||||||||||
| RefSeq (mRNA) | NM_003771 | NM_001174099 | |||||||||||
| RefSeq (protein) | NP_003762 | NP_001167570 | |||||||||||
| Location (UCSC) | Chr 17: 39.64 – 39.65 Mb | Chr 11: 100.1 – 100.11 Mb | |||||||||||
| PubMed search | |||||||||||||
Keratin, type I cuticular Ha6 is a protein that in humans is encoded by the KRT36 gene.[1][2][3]
The protein encoded by this gene is a member of the keratin gene family. This type I hair keratin is an acidic protein which heterodimerizes with type II keratins to form hair and nails. The type I hair keratins are clustered in a region of chromosome 17q12-q21 and have the same direction of transcription.[3]
References
- ↑ Rogers MA, Winter H, Wolf C, Heck M, Schweizer J (Nov 1998). "Characterization of a 190-kilobase pair domain of human type I hair keratin genes". J Biol Chem 273 (41): 26683–91. doi:10.1074/jbc.273.41.26683. PMID 9756910.
- ↑ Schweizer J, Bowden PE, Coulombe PA, Langbein L, Lane EB, Magin TM, Maltais L, Omary MB, Parry DA, Rogers MA, Wright MW (Jul 2006). "New consensus nomenclature for mammalian keratins". J Cell Biol 174 (2): 169–74. doi:10.1083/jcb.200603161. PMC 2064177. PMID 16831889.
- ↑ 3.0 3.1 "Entrez Gene: KRT36 keratin 36".
Further reading
- Fuchs E, Weber K (1994). "Intermediate filaments: structure, dynamics, function, and disease.". Annu. Rev. Biochem. 63: 345–82. doi:10.1146/annurev.bi.63.070194.002021. PMID 7979242.
- Yu J, Yu DW, Checkla DM et al. (1993). "Human hair keratins.". J. Invest. Dermatol. 101 (1 Suppl): 56S–59S. doi:10.1111/1523-1747.ep12362635. PMID 7686952.
- Ewing RM, Chu P, Elisma F et al. (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry.". Mol. Syst. Biol. 3 (1): 89. doi:10.1038/msb4100134. PMC 1847948. PMID 17353931.
- Olsen JV, Blagoev B, Gnad F et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.". Cell 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.
- Strausberg RL, Feingold EA, Grouse LH et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Langbein L, Rogers MA, Winter H et al. (1999). "The catalog of human hair keratins. I. Expression of the nine type I members in the hair follicle.". J. Biol. Chem. 274 (28): 19874–84. doi:10.1074/jbc.274.28.19874. PMID 10391933.
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