KIF20A
| Kinesin family member 20A | |||||||||||||
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| Identifiers | |||||||||||||
| Symbols | KIF20A ; MKLP2; RAB6KIFL | ||||||||||||
| External IDs | OMIM: 605664 MGI: 1201682 HomoloGene: 38093 GeneCards: KIF20A Gene | ||||||||||||
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| RNA expression pattern | |||||||||||||
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| More reference expression data | |||||||||||||
| Orthologs | |||||||||||||
| Species | Human | Mouse | |||||||||||
| Entrez | 10112 | 19348 | |||||||||||
| Ensembl | ENSG00000112984 | ENSMUSG00000003779 | |||||||||||
| UniProt | O95235 | P97329 | |||||||||||
| RefSeq (mRNA) | NM_005733 | NM_001166406 | |||||||||||
| RefSeq (protein) | NP_005724 | NP_001159878 | |||||||||||
| Location (UCSC) | Chr 5: 137.51 – 137.52 Mb | Chr 18: 34.62 – 34.63 Mb | |||||||||||
| PubMed search | |||||||||||||
Kinesin-like protein KIF20A is a protein that in humans is encoded by the KIF20A gene.[1][2][3]
Interactions
KIF20A has been shown to interact with RAB6A.[4][5]
References
- ↑ Miki H, Setou M, Kaneshiro K, Hirokawa N (June 2001). "All kinesin superfamily protein, KIF, genes in mouse and human". Proc Natl Acad Sci U S A 98 (13): 7004–11. doi:10.1073/pnas.111145398. PMC 34614. PMID 11416179.
- ↑ Lai F, Fernald AA, Zhao N, Le Beau MM (July 2000). "cDNA cloning, expression pattern, genomic structure and chromosomal location of RAB6KIFL, a human kinesin-like gene". Gene 248 (1–2): 117–25. doi:10.1016/S0378-1119(00)00135-9. PMID 10806357.
- ↑ "Entrez Gene: KIF20A kinesin family member 20A".
- ↑ Echard A, Jollivet F, Martinez O, Lacapère JJ, Rousselet A, Janoueix-Lerosey I et al. (January 1998). "Interaction of a Golgi-associated kinesin-like protein with Rab6". Science 279 (5350): 580–5. doi:10.1126/science.279.5350.580. PMID 9438855. Vancouver style error (help)
- ↑ Echard A, Opdam FJ, de Leeuw HJ, Jollivet F, Savelkoul P, Hendriks W et al. (November 2000). "Alternative splicing of the human Rab6A gene generates two close but functionally different isoforms". Mol. Biol. Cell 11 (11): 3819–33. doi:10.1091/mbc.11.11.3819. PMC 15039. PMID 11071909.
Further reading
- Echard A, Jollivet F, Martinez O, Lacapère JJ, Rousselet A, Janoueix-Lerosey I et al. (1998). "Interaction of a Golgi-associated kinesin-like protein with Rab6". Science 279 (5350): 580–5. doi:10.1126/science.279.5350.580. PMID 9438855. Vancouver style error (help)
- Horrevoets AJ, Fontijn RD, van Zonneveld AJ, de Vries CJ, ten Cate JW, Pannekoek H (1999). "Vascular endothelial genes that are responsive to tumor necrosis factor-alpha in vitro are expressed in atherosclerotic lesions, including inhibitor of apoptosis protein-1, stannin, and two novel genes". Blood 93 (10): 3418–31. PMID 10233894.
- Opdam FJ, Echard A, Croes HJ, van den Hurk JA, van de Vorstenbosch RA, Ginsel LA et al. (2000). "The small GTPase Rab6B, a novel Rab6 subfamily member, is cell-type specifically expressed and localised to the Golgi apparatus". J. Cell. Sci. 113 (15): 2725–35. PMID 10893188.
- Hill E, Clarke M, Barr FA (2000). "The Rab6-binding kinesin, Rab6-KIFL, is required for cytokinesis". EMBO J. 19 (21): 5711–9. doi:10.1093/emboj/19.21.5711. PMC 305783. PMID 11060022.
- Echard A, Opdam FJ, de Leeuw HJ, Jollivet F, Savelkoul P, Hendriks W et al. (2001). "Alternative Splicing of the Human Rab6A Gene Generates Two Close but Functionally Different Isoforms". Mol. Biol. Cell 11 (11): 3819–33. doi:10.1091/mbc.11.11.3819. PMC 15039. PMID 11071909.
- Hartley JL, Temple GF, Brasch MA (2001). "DNA Cloning Using In Vitro Site-Specific Recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948. PMID 11076863.
- Nagura M, Nagao Y, Takita J, Igarashi T, LeGuern E, Hayashi Y (2003). "The kinesin superfamily protein Rab6KIFL is not involved in the pathophysiology of Charcot-Marie-Tooth disease type 4C". Int. J. Mol. Med. 11 (1): 45–7. doi:10.3892/ijmm.11.1.45. PMID 12469216.
- Neef R, Preisinger C, Sutcliffe J, Kopajtich R, Nigg EA, Mayer TU et al. (2003). "Phosphorylation of mitotic kinesin-like protein 2 by polo-like kinase 1 is required for cytokinesis". J. Cell Biol. 162 (5): 863–75. doi:10.1083/jcb.200306009. PMC 2172827. PMID 12939256.
- Gruneberg U, Neef R, Honda R, Nigg EA, Barr FA (2004). "Relocation of Aurora B from centromeres to the central spindle at the metaphase to anaphase transition requires MKlp2". J. Cell Biol. 166 (2): 167–72. doi:10.1083/jcb.200403084. PMC 2172317. PMID 15263015.
- Wiemann S, Arlt D, Huber W, Wellenreuther R, Schleeger S, Mehrle A et al. (2004). "From ORFeome to Biology: A Functional Genomics Pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930. PMID 15489336.
- Taniuchi K, Nakagawa H, Nakamura T, Eguchi H, Ohigashi H, Ishikawa O et al. (2005). "Down-regulation of RAB6KIFL/KIF20A, a kinesin involved with membrane trafficking of discs large homologue 5, can attenuate growth of pancreatic cancer cell". Cancer Res. 65 (1): 105–12. PMID 15665285.
- Mehrle A, Rosenfelder H, Schupp I, del Val C, Arlt D, Hahne F et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC 1347501. PMID 16381901.
- Nousiainen M, Silljé HH, Sauer G, Nigg EA, Körner R (2006). "Phosphoproteome analysis of the human mitotic spindle". Proc. Natl. Acad. Sci. U.S.A. 103 (14): 5391–6. doi:10.1073/pnas.0507066103. PMC 1459365. PMID 16565220. Vancouver style error (help)
- Olsen JV, Blagoev B, Gnad F, Macek B, Kumar C, Mortensen P et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.
External links
- KIF20A human gene location in the UCSC Genome Browser.
- KIF20A human gene details in the UCSC Genome Browser.