Joseph Sambrook

Joseph Sambrook
Born 1 March 1939
Liverpool, England
Residence Melbourne, Australia
Fields Molecular biology
Institutions MRC Laboratory of Molecular Biology, Salk Institute for Biological Studies, Cold Spring Harbor Laboratory, University of Texas Southwestern Medical Center, Peter MacCallum Cancer Centre
Alma mater Australian National University
Known for Laboratory manual Molecular Cloning, work on oncoviruses
Notable awards Victorian Government Leadership and Innovation Award, Elected Fellow of the Australian Academy of Sciences and the Royal Society

Joseph Frank Sambrook (born 1 March 1939 in Liverpool, England) is a British molecular biologist known for his studies of DNA oncoviruses and the molecular biology of normal and cancerous cells. He currently resides in Melbourne, Australia with his wife and daughter.

Education and early career

Sambrook was educated at the University of Liverpool (BSc (hons) 1962) and obtained his PhD at the Australian National University in 1966. He did postdoctoral research at the MRC Laboratory of Molecular Biology (1966–67) and the Salk Institute for Biological Studies (1967–69). In 1969 he was hired by James D. Watson to work at the Cold Spring Harbor Laboratory in New York. Watson has been reported to say this was the best hiring decision he ever made. Joe was responsible for creating a combative creative environment at CSHL that fomented discovery. Subsequently he worked at the University of Texas Southwestern Medical Center (Dallas).[1]

Achievements

Sambrook is best known for his studies on DNA tumor viruses and the molecular biology of normal and neoplastic cells. His Tumour Virus Group at Cold Spring Harbor identified and mapped all of the major genes of adenoviruses and SV40, determined their transcriptional control in infected and transformed cells, and elucidated the mechanism of integration of these viruses into the genome of the host cell. He has also made important contributions to the understanding of intracellular traffic and protein folding and is an influential leader in the field of the molecular genetics of human cancer.

Sambrook is a former Director of Research at the Peter MacCallum Cancer Centre in Melbourne[2][3] and is an elected Fellow of the Australian Academy of Sciences[4] and the Royal Society.[5] He was the founder and director of the Kathleen Cunningham Consortium for research into familial breast cancer, KConFab, that was established in 1995. [6]

Sambrook has published three editions of the best-selling, highly influential laboratory manual Molecular Cloning.[7] He is also co-editor of Inspiring Science: Jim Watson and the Age of DNA and Life Illuminated: Selected Papers from Cold Spring Harbor Volume 2, 1972–1994. All three books were published by Cold Spring Harbor Laboratory Press.

In 2009 he was awarded the "Victorian Government Leadership and Innovation Award".[1]

References

  1. ↑ 1.0 1.1 ""Thank You" Day Awards, BMW Edge, Federation Square, Melbourne 2009". thankyouday.org. 20 November 2010. Retrieved 11 April 2010.
  2. ↑ "Peter Mac - Our History". petermac.org. Retrieved 11 April 2010.
  3. ↑ "AAS-President's Notes 10". Australian Academy of Science. 24 March 2000. Retrieved 11 April 2010.
  4. ↑ "AAS-President's Notes 11". Australian Academy of Science. 20 April 2000. Retrieved 11 April 2010.
  5. ↑ "Prof Joseph Sambrook". The University of Melbourne. Retrieved 12 April 2010.
  6. ↑ "kConFab – The Kathleen Cuningham Foundation Consortium for Research into Familial Brest Cancer". nhmrc.gov.au. Retrieved 11 April 2010.
  7. ↑ "Molecular Cloning: A Laboratory Manual(Third Edition)". Cold Spring Harbor Laboratory Press. Retrieved 11 April 2010.