José Antonio
José Antonio is a common pairing of personal names in Spanish and Portuguese, and may refer to:
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- José Antonio Alonso (b. 1960), Spanish politician
- José António Bargiela (b. 1957), Portuguese footballer
- José Antonio Cabrera (b. 1768), Argentine statesman
- José Antonio Delgado (b. 1965), Venezuelan mountaineer
- José Antonio Díaz (disambiguation)
- José Antonio Estudillo (b. 1805), Californio settler of San Diego, California
- José Antonio Fernández (b. 1954), Mexican businessman
- José Antonio García (b. 1992), Mexican footballer
- José Antonio García Belaúnde (b. 1948), Peruvian diplomat
- José Antonio Gómez (b. 1953), Chilean lawyer
- José Antonio González (disambiguation)
- José Antonio Martínez (b. 1793), New Mexican priest
- José Antonio Muñoz (b. 1942), Argentine artist
- José Antonio Primo de Rivera (b. 1903), Spanish lawyer
- José Antonio Rodríguez (disambiguation)
- José Antonio Romero (b. 1968), Mexican sprint canoer