John Spence

John Spence may refer to:

• John S. Spence (1788–1880), American Senator from Maryland
• John Spence (politician) (1920–1986), British Conservative MP 1970–1986
• John Spence (Trinidad politician) (1929–2013), Trinidadian botanist and politician
• John Spence (frogman) (1918–2013), American World War II veteran, first American combat frogman
• John Spence (musician) (1969–1987), founding member of the band No Doubt
• John Selby Spence (Catholic bishop) (1909–1973)

See also

• Jonathan Spence, British-born historian
• John Spence Community High School, a secondary school in Preston, Tyne and Wear, England