John Graham White

John White
Born John Graham White
1943 (age 71–72) [1]
Wales
Fields
Institutions
Alma mater
Thesis Computer aided reconstruction of the nervous system of Caenorhabditis elegans (1975)
Doctoral students Richard Durbin[3]
Other notable students Julie Ahringer[4]
Known for Research using Caenorhabditis elegans
Notable awards Mullard Award (1994)
Website
www.engr.wisc.edu/bme/faculty/white_john.html

John Graham White is a Professor Emeritus of Anatomy and Molecular Biology at the University of Wisconsin–Madison.[1][2][5][6][7][8]

Education

White was educated at Brunel University, where he was awarded an undergraduate degree in Physics in 1969.[1] He went on to study for his Ph.D.[9] at University of Cambridge in 1975 for work on computer-aided reconstruction of the nervous system of Caenorhabditis elegans.[1]

Research

After working at the Laboratory of Molecular Biology, White moved to the University of Wisconsin–Madison in 1993.[1] White's research investigates cell division in the nematode Caenorhabditis elegans.[10][11][12][13][14] With collaborators Sydney Brenner,[15][16] John Sulston[17] and others, White co-developed confocal microscopy and mapped the complete nervous system of Caenorhabditis elegans, consisting of 302 neurons and over 7000 synapses. The study was published in 1986 by the Philosophical Transactions of the Royal Society of London,[16] and is considered to be the first work in the emerging field of connectomes. More recently his research uses:

“ two collaborative but distinct laboratories, one a biological laboratory that investigates cell division in the nematode Caenorhabditis elegans, and the other an interdisciplinary Biophotonics Instrumentation laboratory that develops new computational and optical techniques for live cell studies.[2] ”

Personal life

White retired in 2008,[1] since when he has been Professor Emeritus.

References

  1. ↑ 1.0 1.1 1.2 1.3 1.4 1.5 1.6 1.7 White, J. G. (2013). "Getting into the mind of a worm—a personal view". WormBook: 1–10. doi:10.1895/wormbook.1.158.1. PMID 23801597.
  2. ↑ 2.0 2.1 2.2 "White, John - UW-Engineering Directory, College of Engineering @ The University of Wisconsin-Madison". Archived from the original on 2013-12-11.
  3. ↑ Durbin, Richard (1987). Studies on the development and organisation of the nervous system of Caenorhabditis elegans (PhD thesis). University of Cambridge.
  4. ↑ Malone, C. J.; Misner, L.; Le Bot, N.; Tsai, M. C.; Campbell, J. M.; Ahringer, J.; White, J. G. (2003). "The C. Elegans hook protein, ZYG-12, mediates the essential attachment between the centrosome and nucleus". Cell 115 (7): 825–836. doi:10.1016/S0092-8674(03)00985-1. PMID 14697201.
  5. ↑ John Graham White's publications indexed by the Scopus bibliographic database, a service provided by Elsevier.
  6. ↑ Squirrell, J. M.; Wokosin, D. L.; White, J. G.; Bavister, B. D. (1999). "Long-term two-photon fluorescence imaging of mammalian embryos without compromising viability". Nature Biotechnology 17 (8): 763–767. doi:10.1038/11698. PMID 10429240.
  7. ↑ Kimble, J. E.; White, J. G. (1981). "On the control of germ cell development in Caenorhabditis elegans". Developmental biology 81 (2): 208–219. doi:10.1016/0012-1606(81)90284-0. PMID 7202837.
  8. ↑ Chalfie, M.; Eddy, S.; Hengartner, M. O.; Hodgkin, J.; Kohara, Y.; Plasterk, R. H.; Waterston, R. H.; White, J. G. (1995). "Genome maps. VI. Caenorhabditis elegans. Wall chart". Science 270 (5235): 415–430. doi:10.1126/science.270.5235.410. PMID 7569996.
  9. ↑ White, John (1975). Computer aided reconstruction of the nervous system of Caenorhabditis elegans (PhD thesis). University of Cambridge.
  10. ↑ Hyman, A. A.; White, J. G. (1987). "Determination of cell division axes in the early embryogenesis of Caenorhabditis elegans". The Journal of cell biology 105 (5): 2123–2135. doi:10.1083/jcb.105.5.2123. PMC 2114830. PMID 3680373.
  11. ↑ Podbilewicz, B.; White, J. G. (1994). "Cell fusions in the developing epithelial of C. Elegans". Developmental biology 161 (2): 408–424. doi:10.1006/dbio.1994.1041. PMID 8313992.
  12. ↑ White, J.; Strome, S. (1996). "Cleavage plane specification in C. Elegans: How to divide the spoils". Cell 84 (2): 195–198. doi:10.1016/s0092-8674(00)80974-5. PMID 8565065.
  13. ↑ O'Connell, K. F.; Leys, C. M.; White, J. G. (1998). "A genetic screen for temperature-sensitive cell-division mutants of Caenorhabditis elegans". Genetics 149 (3): 1303–1321. PMC 1460235. PMID 9649522.
  14. ↑ Hird, S. N.; White, J. G. (1993). "Cortical and cytoplasmic flow polarity in early embryonic cells of Caenorhabditis elegans". The Journal of cell biology 121 (6): 1343–1355. doi:10.1083/jcb.121.6.1343. PMC 2119718. PMID 8509454.
  15. ↑ White, J. G.; Southgate, E.; Thomson, J. N.; Brenner, S. (1976). "The structure of the ventral nerve cord of Caenorhabditis elegans". Philosophical transactions of the Royal Society of London. Series B, Biological sciences 275 (938): 327–348. doi:10.1098/rstb.1976.0086. PMID 8806.
  16. ↑ 16.0 16.1 White, J. G.; Southgate, E.; Thomson, J. N.; Brenner, S. (1986). "The structure of the nervous system of the nematode Caenorhabditis elegans". Philosophical transactions of the Royal Society of London. Series B, Biological sciences 314 (1165): 1–340. doi:10.1098/rstb.1986.0056. PMID 22462104.
  17. ↑ Sulston, J.; Schierenberg, E.; White, J. G.; Thomson, J. (1983). "The embryonic cell lineage of the nematode Caenorhabditis elegans". Developmental biology 100 (1): 64–119. doi:10.1016/0012-1606(83)90201-4. PMID 6684600.