James Duke
James Duke is the name of:
- James Buchanan Duke (1856–1925), U.S. tobacco and electric power magnate
- James A. Duke (born 1933), ethnobotanist
- Sir James Duke, 1st Baronet (1792–1873), British Liberal Party Member of Parliament (MP) for Boston 1837–1849 and City of London 1849–65
- Sir James Duke, 2nd Baronet, of the Duke baronets
- See also
- Jamie Dukes, former American football player