JWH-185
 | |
| Systematic (IUPAC) name | |
|---|---|
| 3-[(4-methoxy-1-naphthalenyl)methyl]-1-pentyl-1H-indole | |
| Clinical data | |
| |
| Identifiers | |
| 619294-39-2 | |
| Chemical data | |
| Formula | C25H27NO |
| 357.49 g/mol | |
JWH-185 is a synthetic cannabinoid receptor ligand from the naphthoylindole family. It is the carbonyl-reduced derivative of related compound JWH-081. The binding affinity of JWH-185 for the CB1 receptor is reported as Ki = 17 ± 3 nM.[1]
See also
References
- ↑ Huffman JW, Mabon R, Wu M-J, Lu J, Hart R, Hurst DP, Reggio PH, Wiley JL, Martin BR (2003). "3-Indolyl-1-naphthylmethanes: new cannabimimetic indoles provide evidence for aromatic stacking interactions with the CB1 cannabinoid receptor". Bioorg. Med. Chem. 11 (4): 539–549. doi:10.1016/s0968-0896(02)00451-0.