JWH-116
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| Systematic (IUPAC) name | |
|---|---|
| (2-ethyl-1-pentyl-1H-indol-3-yl)-1-naphthalenylmethanone | |
| Clinical data | |
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| Identifiers | |
| 619294-64-3 | |
| ChemSpider | 29341485 |
| Chemical data | |
| Formula | C26H27NO |
| 369.50 g/mol | |
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SMILES
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JWH-116 is a synthetic cannabinoid receptor ligand from the naphthoylindole family. It is the indole 2-ethyl derivative of related compound JWH-018. The binding affinity of JWH-116 for the CB1 receptor is reported as Ki = 52 ± 5 nM.[1]
See also
References
- ↑ Huffman JW, Mabon R, Wu M-J, Lu J, Hart R, Hurst DP, Reggio PH, Wiley JL, Martin BR (2003). "3-Indolyl-1-naphthylmethanes: new cannabimimetic indoles provide evidence for aromatic stacking interactions with the CB1 cannabinoid receptor". Bioorg. Med. Chem. 11 (4): 539–549. doi:10.1016/s0968-0896(02)00451-0.