JCO
JCO as an acronym may stand for:
- JCO (company), a Japanese nuclear fuel cycle company involved in the Tokaimura nuclear accident
- Jewish Combat Organization, a Jewish resistance group during World War II
- Journal of Clinical Oncology, a leading medical journal
- Joyce Carol Oates, American author
- Junior Commissioned Officer, a group of military ranks in the armies of India and Pakistan
- Joint Commission Observers