Isodesmosine

Isodesmosine
Identifiers
991-01-5 Yes
ChEBI CHEBI:64366 
PubChem 13811
Properties
C24H40N5O8
Molar mass 526.603 g/mol
Except where noted otherwise, data is given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
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Infobox references

Isodesmosine is a lysine derivative found in elastin. Isodesmosine is an isomeric pyridinium-based amino acid resulting from the condensation of four lysine residues between elastin proteins by lysyl-oxidase. These represent ideal biomarkers for monitoring elastin turnover because these special cross-links are only found in mature elastin in mammals.[1]

  1. [Miao M, Bruce AE, Bhanji T, et al. Differential expression of two tropoelastin genes in zebrafish. Matrix Biol 2007;26:115e24]

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