Impromidine

Impromidine

Systematic (IUPAC) name
N-[3-(1H-imidazol-4-yl)-propyl]-N'-(2-{[(4-methyl-1H-imidazol-5-yl)methyl]thio}ethyl)guanidine
Clinical data
Identifiers
CAS Registry Number	55273-05-7 Y
ATC code	None
PubChem	CID 41376
IUPHAR ligand	1226
ChemSpider	37757 N
UNII	931L4X5WMM N
ChEMBL	CHEMBL12608 N
Chemical data
Formula	C14H23N7S
Molecular mass	321.44 g/mol
SMILES Cc2ncnc2CSCCNC(N)=NCCCc1cncn1
InChI InChI=1S/C14H23N7S/c1-11-13(21-10-19-11)8-22-6-5-18-14(15)17-4-2-3-12-7-16-9-20-12/h7,9-10H,2-6,8H2,1H3,(H,16,20)(H,19,21)(H3,15,17,18)  N Key:MURRAGMMNAYLNA-UHFFFAOYSA-N  N
N (what is this?)  (verify)

Impromidine (INN) is a highly potent and specific histamine H₂ receptor agonist.^[1]

It has been used diagnostically as a gastric secretion indicator.

See Histamine agonists.

References

1. ↑ Durant G, Duncan W, Ganellin C, Parsons M, Blakemore R, Rasmussen A (1978). "Impromidine (SK&F 92676) is a very potent and specific agonist for histamine H2 receptors". Nature 276 (5686): 403–5. doi:10.1038/276403a0. PMID 714166.