Imidapril

Imidapril
Systematic (IUPAC) name

(4S)-3-[(2S)-2-{[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino}propanoyl]-1-methyl-2-oxoimidazolidine-4-carboxylic acid
Clinical data
AHFS/Drugs.com	International Drug Names
Identifiers
CAS Registry Number	89371-37-9^Y
ATC code	C09AA16
PubChem	CID 5464343
ChemSpider	4576628^N
UNII	BW7H1TJS22^Y
KEGG	D08068^Y
ChEMBL	CHEMBL317094^N
Chemical data
Formula	C₂₀H₂₇N₃O₆
Molecular mass	405.444 g/mol
SMILES O=C(O)[C@H]2N(C(=O)[C@@H](N[C@H](C(=O)OCC)CCc1ccccc1)C)C(=O)N(C)C2
InChI InChI=1S/C20H27N3O6/c1-4-29-19(27)15(11-10-14-8-6-5-7-9-14)21-13(2)17(24)23-16(18(25)26)12-22(3)20(23)28/h5-9,13,15-16,21H,4,10-12H2,1-3H3,(H,25,26)/t13-,15-,16-/m0/s1 ^N Key:KLZWOWYOHUKJIG-BPUTZDHNSA-N ^N
N (what is this?) (verify)

Imidapril (INN) is an ACE inhibitor used as an antihypertensive drug and for the treatment of chronic heart failure.^[1]

References

↑ Robinson, D. M.; Curran, M. P.; Lyseng-Williamson, K. A. (2007). "Imidapril: A review of its use in essential hypertension, Type 1 diabetic nephropathy and chronic heart failure". Drugs 67 (9): 1359–1378. doi:10.2165/00003495-200767090-00008. PMID 17547476.

Antihypertensives: agents acting on the renin–angiotensin system (C09)

ACE inhibitors
("-pril")

Phosphonate-containing: Fosinopril (+HCT)

AIIRAs/
("-sartan")

Renin inhibitors/
("-kiren")

Aliskiren (+amlodipine, +amlodipine and HCT)
Remikiren^§

^#WHO-EM
^‡Withdrawn from market
Clinical trials:
- ^†Phase III
- ^§Never to phase III

Index of the circulatory system

Description	Anatomy Arteries head and neck arms chest abdomen legs Veins head and neck arms chest abdomen and pelvis legs Development Cells Physiology proteins

Disease	Congenital Neoplasms and cancer Lymphatic vessels Injury Vasculitis Other Symptoms and signs eponymous

Treatment	Procedures Drugs beta blockers channel blockers diuretics nonsympatholytic vasodilatory antihypertensives peripheral vasodilators renin–angiotensin system sympatholytic antihypertensives vasoprotectives