ITGB3BP

Integrin beta 3 binding protein (beta3-endonexin)
Identifiers
SymbolsITGB3BP ; CENP-R; CENPR; HSU37139; NRIF3; TAP20
External IDsOMIM: 605494 MGI: 1914983 HomoloGene: 8617 GeneCards: ITGB3BP Gene
RNA expression pattern
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez2342167733
EnsemblENSG00000142856ENSMUSG00000028549
UniProtQ13352Q9CQ82
RefSeq (mRNA)NM_001206739NM_026348
RefSeq (protein)NP_001193668NP_080624
Location (UCSC)Chr 1:
63.91 – 64.06 Mb
Chr 4:
99.77 – 99.93 Mb
PubMed search

Centromere protein R is a protein that in humans is encoded by the ITGB3BP gene.[1][2][3]

Interactions

ITGB3BP has been shown to interact with:

References

  1. 1.0 1.1 Shattil SJ, O'Toole T, Eigenthaler M, Thon V, Williams M, Babior BM, Ginsberg MH (December 1995). "Beta 3-endonexin, a novel polypeptide that interacts specifically with the cytoplasmic tail of the integrin beta 3 subunit". J Cell Biol 131 (3): 807–16. doi:10.1083/jcb.131.3.807. PMC 2120613. PMID 7593198.
  2. 2.0 2.1 2.2 Li D, Desai-Yajnik V, Lo E, Schapira M, Abagyan R, Samuels HH (February 2000). "NRIF3 is a novel coactivator mediating functional specificity of nuclear hormone receptors". Mol Cell Biol 19 (10): 7191–202. PMC 84712. PMID 10490654.
  3. "Entrez Gene: ITGB3BP integrin beta 3 binding protein (beta3-endonexin)".
  4. Fujimoto TT, Katsutani S, Shimomura T, Fujimura K (January 2002). "Novel alternatively spliced form of beta(3)-endonexin". Thromb. Res. 105 (1): 63–70. doi:10.1016/s0049-3848(01)00405-4. PMID 11864709.
  5. Ohtoshi A, Maeda T, Higashi H, Ashizawa S, Yamada M, Hatakeyama M (January 2000). "beta3-endonexin as a novel inhibitor of cyclin A-associated kinase". Biochem. Biophys. Res. Commun. 267 (3): 947–52. doi:10.1006/bbrc.1999.2007. PMID 10673397.
  6. Besta F, Massberg S, Brand K, Müller E, Page S, Grüner S, Lorenz M, Sadoul K, Kolanus W, Lengyel E, Gawaz M (October 2002). "Role of beta(3)-endonexin in the regulation of NF-kappaB-dependent expression of urokinase-type plasminogen activator receptor". J. Cell. Sci. 115 (Pt 20): 3879–88. doi:10.1242/jcs.00081. PMID 12244126.
  7. 7.0 7.1 Li D, Wang F, Samuels HH (December 2001). "Domain structure of the NRIF3 family of coregulators suggests potential dual roles in transcriptional regulation". Mol. Cell. Biol. 21 (24): 8371–84. doi:10.1128/MCB.21.24.8371-8384.2001. PMC 100002. PMID 11713274.


Further reading