IFT74
| Intraflagellar transport 74 homolog (Chlamydomonas) | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||||||
| Symbols | IFT74 ; CCDC2; CMG-1; CMG1 | ||||||||||||
| External IDs | OMIM: 608040 MGI: 1914944 HomoloGene: 11831 GeneCards: IFT74 Gene | ||||||||||||
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| Orthologs | |||||||||||||
| Species | Human | Mouse | |||||||||||
| Entrez | 80173 | 67694 | |||||||||||
| Ensembl | ENSG00000096872 | ENSMUSG00000028576 | |||||||||||
| UniProt | Q96LB3 | Q8BKE9 | |||||||||||
| RefSeq (mRNA) | NM_001099222 | NM_026319 | |||||||||||
| RefSeq (protein) | NP_001092692 | NP_080595 | |||||||||||
| Location (UCSC) | Chr 9: 26.95 – 27.06 Mb | Chr 4: 94.61 – 94.69 Mb | |||||||||||
| PubMed search | |||||||||||||
Intraflagellar transport protein 74 homolog (IFT74), also known as coiled-coil domain-containing protein 2 (CCDC2) and capillary morphogenesis gene 1 protein (CMG1), is a protein that in humans is encoded by the IFT74 gene.[1][2]
BCMG1 is upregulated by umbilical vein endothelial cells during capillary morphogenesis.[2]
References
- ↑ "Entrez Gene: intraflagellar transport 74 homolog (Chlamydomonas)".
- ↑ 2.0 2.1 Bell SE, Mavila A, Salazar R, Bayless KJ, Kanagala S, Maxwell SA, Davis GE (August 2001). "Differential gene expression during capillary morphogenesis in 3D collagen matrices: regulated expression of genes involved in basement membrane matrix assembly, cell cycle progression, cellular differentiation and G-protein signaling". J. Cell. Sci. 114 (Pt 15): 2755–73. PMID 11683410.
Further reading
- Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
- Xiao S, Sato C, Kawarai T, et al. (2008). "Genetic studies of GRN and IFT74 in amyotrophic lateral sclerosis.". Neurobiol. Aging 29 (8): 1279–82. doi:10.1016/j.neurobiolaging.2007.02.022. PMID 17383054.
- Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.". Gene 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
- Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: Large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.