Hypothalamic-pituitary hormone
Hypothalamic-pituitary hormones refer to a class of hormones that are produced by the hypothalamus and pituitary gland. Although the organs in which they are produced are relatively small, the effects of these hormones cascade throughout the body.
| HPT axis | HPA axis | HPG axis | Growth | Lactation | |
|---|---|---|---|---|---|
| Hypothalamic hormone | TRH | CRH | GnRH | GHRH | Dopamine (inhibitor) |
| Pituitary hormone | TSH | ACTH | LH and FSH | GH | Prolactin |
| End organ | Thyroid | Adrenal | Gonads (Testes or ovaries) | Liver | Breast gland |
| Product | Thyroxine | Cortisol | Testosterone or estradiol | IGF-1 | Milk (no feedback) |
It is possible for the function of these hormones to be altered by physical activity.[2]
References
- ↑ Melmed S, Jameson JL (2005). "Disorders of the anterior pituitary and hypothalamus". In Kasper DL, Braunwald E, Fauci AS et al. Harrison's Principles of Internal Medicine (16th ed.). New York, NY: McGraw-Hill. pp. 2076–97. ISBN 0-07-139140-1.
- ↑ Bobbert T, Brechtel L, Mai K et al. (November 2005). "Adaptation of the hypothalamic-pituitary hormones during intensive endurance training". Clinical endocrinology 63 (5): 530–6. doi:10.1111/j.1365-2265.2005.02377.x. PMID 16268805.
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