Hydroxypethidine

Hydroxypethidine
Systematic (IUPAC) name
Ethyl 4-(3-hydroxyphenyl)-1-methyl-piperidine-4-carboxylate
Clinical data
Identifiers
468-56-4
None
PubChem CID 61120
ChemSpider 55068 Yes
UNII W1J43H2B3K Yes
Chemical data
Formula C15H21NO3
263.332 g/mol
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Hydroxypethidine (Bemidone) is an opioid analgesic that is an analogue of pethidine (meperidine). Hydroxypethidine is significantly less potent than meperidine as an analgesic, (0.3x meperidine in potency) although it also has NMDA antagonist properties like its close relative ketobemidone.[1]

Hydroxypethidine has similar effects to other opioids, and produces analgesia, sedation and euphoria. Side effects can include itching, nausea and potentially serious respiratory depression which can be life-threatening.

See also

References

  1. Isbell Harris. The addiction liability of some analogues of meperidine. Journal of Pharmacology And Experimental Therapeutics, 1949; 97(2): 182-190