Hemin
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Systematic (IUPAC) name | |
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Chloro[3,7,12,17-tetramethyl-8,13-divinylporphyrin-2,18-dipropanoato(2−)]iron(III) | |
Clinical data | |
AHFS/Drugs.com | Consumer Drug Information |
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Intravenous infusion | |
Identifiers | |
16009-13-5 ![]() | |
B06AB01 | |
PubChem | CID 5318002 |
ChemSpider |
21160444 ![]() |
UNII |
743LRP9S7N ![]() |
ChEMBL |
CHEMBL1628226 ![]() |
Chemical data | |
Formula | C34H32ClFeN4O4 |
651.94 g/mol | |
SMILES
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Hemin (trade name Panhematin) is an iron-containing porphyrin.[1] More specifically, it is Protoporphyrin IX containing a ferric iron ion (Heme B) with a chloride ligand.
It is used in the management of porphyria attacks, particularly in acute intermittent porphyria.
It is sometimes distinguished from Hematin which has a hydroxide ligand in place of the chloride. However, the terms are sometimes equated.[2]
Hematin is considered the "X factor" required for the growth of Haemophilus influenzae.[3]
See also
References
- ↑ "hemin" at Dorland's Medical Dictionary
- ↑ "hematin" at Dorland's Medical Dictionary
- ↑ Sherris, John C.; Ryan, Kenneth J.; Ray, C. L. (2004). Sherris medical microbiology: an introduction to infectious diseases. New York: McGraw-Hill. p. 395. ISBN 0-8385-8529-9.
External links
- Information from the American Porphyria Foundation, including emergency delivery information
- Hemin at RxList
- Hemin at the US National Library of Medicine Medical Subject Headings (MeSH)