Harmalol

Harmalol

Identifiers
ChemSpider	4510170
EC number	208-375-4
InChI InChI=1S/C12H12N2O/c1-7-12-10(4-5-13-7)9-3-2-8(15)6-11(9)14-12/h2-3,6,13-14H,4-5H2,1H3 Key: CRQDWQWZCNKKAC-UHFFFAOYSA-N InChI=1/C12H12N2O/c1-7-12-10(4-5-13-7)9-3-2-8(15)6-11(9)14-12/h2-3,6,13-14H,4-5H2,1H3 Key: CRQDWQWZCNKKAC-UHFFFAOYAP
Jmol-3D images	Image
PubChem	5353656
SMILES O=C/1\C=C2C(\C=C\1)=C3C(\N2)=C(/NCC3)C
Properties
Molecular formula	C12H12N2O
Molar mass	200.24 g·mol−1
Appearance	red solid
Melting point	100 to 105 °C (212 to 221 °F; 373 to 378 K) (trihydrate)[1]
Except where noted otherwise, data is given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
Infobox references

Harmalol is a bio-active beta-carboline and a member of the harmala alkaloids.^[2][3]

References

1. ↑ Thieme Chemistry (Hrsg.): RÖMPP Online – Version 3.37. Georg Thieme Verlag KG, Stuttgart, 27. September 2013.
2. ↑ Sarkar S, Bhadra K (2014). "Binding of alkaloid harmalol to DNA: photophysical and calorimetric approach.". J Photochem Photobiol B 130: 272–80. doi:10.1016/j.jphotobiol.2013.11.021. PMID 24368411. 
3. ↑ El Gendy MA, Soshilov AA, Denison MS, El-Kadi AO (2012). "Harmaline and harmalol inhibit the carcinogen-activating enzyme CYP1A1 via transcriptional and posttranslational mechanisms.". Food Chem Toxicol 50 (2): 353–62. doi:10.1016/j.fct.2011.10.052. PMC 3281145. PMID 22037238.