Haplogroup O-M175

Haplogroup O-M175
Possible time of origin 28,000-41,000 years BP (Scheinfeldt 2006)
Possible place of origin Southeast or East Asia
Ancestor NO
Descendants O-MSY2.2, O-M268, O-M122
Defining mutations M175, P186, P191, P196

In molecular evolution, a haplogroup (from the Greek: ἁπλούς, haploûs, "onefold, single, simple") is a group of similar haplotypes that share a common ancestor having the same single nucleotide polymorphism (SNP) mutation in all haplotypes. Haplogroup O-M175 is a Y-chromosome DNA haplogroup of Southeast Asian and East Asian lineage. It descends from Haplogroup NO.

Origins

Haplogroup O-M175 is a descendant haplogroup of Haplogroup NO-M214, and first appeared according to different theories, either in Southeast Asia (see Rootsi 2006, TMC ?, Shi 2005, and Bradshaw ?) or East Asia (see ISOGG 2012) between 28,000 and 41,000 years before present according to Scheinfeldt 2006 or between 23,000 and 32,000 years before present according to Yan et al. 2013.[1]

Haplogroup O-M175 is one of NO-M214's two branches. The other is Haplogroup N, which is common throughout North Eurasia.

Distribution

This haplogroup appears in 80-90% of most of populations in East Asia and Southeast Asia, and it is almost exclusive to that region: M175 is almost nonexistent in Western Siberia, Western Asia, Europe, Africa, or the Americas, where its presence may be the result of recent migrations. Notably, certain subclades of Haplogroup O-M175 do achieve significant frequencies among some populations of South Asia, Central Asia, and Oceania.

Among the subbranches of Haplogroup O-M175 are O-MSY2.2, O-M268, and O-M122.

Paragroup O-M175

Paragroup O-M175 lineages, which belong to Haplogroup O-M175 but do not display any of the later mutations that define the major subclades O-MSY2.2, O-M268, and O-M122, can be detected at a low frequency among some modern populations of Central Asia and East Asia. A broad survey of Y-chromosome variation among populations of central Eurasia found haplogroup O-M175(xM119,M95,M122) in a significant minority of Koreans (Wells 2001). However, nearly all of these Korean O-M175(xM119,M95,M122) Y-chromosomes may belong to Haplogroup O-M176,[Footnote 1] and later studies do not support the finding of Paragroup O-M175(Xue 2005, Kim 2011). O-M175(xM119,M95,M122) Y-chromosomes that have been found among these populations might therefore belong to Haplogroup O-MSY2.2*(xM119), Haplogroup O-M268*(xM95,M176), or Haplogroup O-M176.

O-F75

O1-MSY2.2 and O2-M268 share a common ancestor, O-F75, approximately 23,400 [95% CI 21,600 to 25,300] YBP.[1]. O-F75, in turn, coalesces to a common ancestor with O3-M122 approximately 24,700 [95% CI 23,000 to 26,500] YBP.[1] Thus, O-F75 existed as a single haplogroup parallel to O3-M122 for a duration of approximately 1,300 years (or anywhere from 0 to 4,900 years considering the 95% CIs and assuming that the phylogeny is correct) before breaking up into its two extant descendant haplogroups, O1-MSY2.2 and O2-M268.

O-MSY2.2

O-M268

O-M122

Found frequently among populations of East Asia, Southeast Asia, and culturally Austronesian regions of Oceania, with a moderate distribution in Central Asia (Shi 2005).

Languages families and genes

The following is a phylogenetic tree of language families and their corresponding SNP markers, or haplogroups, sourced mainly from Edmondson 2007 and Shi 2005. This has been called the "Father Tongue Hypothesis" by George van Driem (vanDriem 2011). It does not appear to account for O-M176, which is found among Japanese, Korean, and Manchurian males.

"Proto- Asiatic" (O-M175) 
 Northern Asiatic (O-M122) 
 Sino-Tibetan (O-M134) 

 Sinitic (O-M117) 



 Tibeto-Burman 



 Hmong–Mien (O-M7) 


 Hmong (Miao) 



 She (Ratliff 1998) 




 Mien (Yao) 




 Southern Asiatic (Austric) 

 Austroasiatic (O-M95) 

 Munda 



 Mon–Khmer 



 Austro-Tai (O-M119) 
 Austronesian 

 Formosan 



 Malayo-Polynesian 



 Tai–Kadai 

 Kadai [Footnote 2] 


 Kam–Tai 

 Kam–Sui 



 Tai 








Phylogenetics

Phylogenetic history

Prior to 2002, there were in academic literature at least seven naming systems for the Y-Chromosome Phylogenetic tree. This led to considerable confusion. In 2002, the major research groups came together and formed the Y-Chromosome Consortium (YCC). They published a joint paper that created a single new tree that all agreed to use. Later, a group of citizen scientists with an interest in population genetics and genetic genealogy formed a working group to create an amateur tree aiming at being above all timely. The table below brings together all of these works at the point of the landmark 2002 YCC Tree. This allows a researcher reviewing older published literature to quickly move between nomenclatures.

YCC 2002/2008 (Shorthand) (α) (β) (γ) (δ) (ε) (ζ) (η) YCC 2002 (Longhand) YCC 2005 (Longhand) YCC 2008 (Longhand) YCC 2010r (Longhand) ISOGG 2006 ISOGG 2007 ISOGG 2008 ISOGG 2009 ISOGG 2010 ISOGG 2011 ISOGG 2012
O-M17526VII1U28Eu16H9IO*OOOOOOOOOO
O-M11926VII1U32Eu16H9HO1*O1aO1aO1aO1aO1aO1aO1aO1aO1aO1a
O-M10126VII1U32Eu16H9HO1aO1a1O1a1aO1a1aO1a1O1a1O1a1aO1a1aO1a1aO1a1aO1a1a
O-M5026VII1U32Eu16H10HO1bO1a2O1a2O1a2O1a2O1a2O1a2O1a2O1a2O1a2O1a2
O-P3126VII1U33Eu16H5IO2*O2O2O2O2O2O2O2O2O2O2
O-M9526VII1U34Eu16H11GO2a*O2aO2aO2aO2aO2aO2aO2aO2aO2a1O2a1
O-M8826VII1U34Eu16H12GO2a1O2a1O2a1O2a1O2a1O2a1O2a1O2a1O2a1O2a1aO2a1a
O-SRY46520VII1U35Eu16H5IO2b*O2bO2bO2bO2bO2bO2bO2bO2bO2bO2b
O-47z5VII1U26Eu16H5IO2b1O2b1aO2b1O2b1O2b1aO2b1aO2b1O2b1O2b1O2b1O2b1
O-M12226VII1U29Eu16H6LO3*O3O3O3O3O3O3O3O3O3O3
O-M12126VII1U29Eu16H6LO3aO3aO3a1O3a1O3a1O3a1O3a1O3a1O3a1O3a1aO3a1a
O-M16426VII1U29Eu16H6LO3bO3bO3a2O3a2O3a2O3a2O3a2O3a2O3a2O3a1bO3a1b
O-M15913VII1U31Eu16H6LO3cO3cO3a3aO3a3aO3a3O3a3O3a3aO3a3aO3a3aO3a3aO3a3a
O-M726VII1U29Eu16H7LO3d*O3cO3a3bO3a3bO3a4O3a4O3a3bO3a3bO3a3bO3a2bO3a2b
O-M11326VII1U29Eu16H7LO3d1O3c1O3a3b1O3a3b1-O3a4aO3a3b1O3a3b1O3a3b1O3a2b1O3a2b1
O-M13426VII1U30Eu16H8LO3e*O3dO3a3cO3a3cO3a5O3a5O3a3cO3a3cO3a3cO3a2c1O3a2c1
O-M11726VII1U30Eu16H8LO3e1*O3d1O3a3c1O3a3c1O3a5aO3a5aO3a3c1O3a3c1O3a3c1O3a2c1aO3a2c1a
O-M16226VII1U30Eu16H8LO3e1aO3d1aO3a3c1aO3a3c1aO3a5a1O3a5a1O3a3c1aO3a3c1aO3a3c1aO3a2c1a1O3a2c1a1

Original Research Publications

The following research teams per their publications were represented in the creation of the YCC Tree.

Phylogenetic trees

This phylogenetic tree of haplogroup O subclades is based on the YCC 2008 tree (Karafet 2008) and subsequent published research.

See also

Genetics

Y-DNA O subclades

  • O-47z
  • O-M101
  • O-M113
  • O-M117
  • O-M119
  • O-M121
  • O-M122
  • O-M134
  • O-M159
  • O-M162
  • O-M164
  • O-M175
  • O-M176
  • O-M50
  • O-M7
  • O-M88
  • O-M95
  • O-MSY2.2
  • O-P31

Y-DNA backbone tree

Evolutionary tree of human Y-chromosome DNA (Y-DNA) haplogroups
MRC Y-ancestor
A00 A0'1'2'3'4
A0 A1'2'3'4
A1 A2'3'4
A2'3 A4=BCDEF
A2 A3 B CDEF
DE CF
D E C F
GHIJKLT
G HIJKLT
H IJKLT
IJ KLT (K)
I J LT(K1) K (K2)
L T MPS (K2b) X (K2a)
MS P NO
M S QR N O
Q R
  1. van Oven M, Van Geystelen A, Kayser M, Decorte R, Larmuseau HD (2014). "Seeing the wood for the trees: a minimal reference phylogeny for the human Y chromosome". Human Mutation 35 (2): 187–91. doi:10.1002/humu.22468. PMID 24166809.

References

Footnotes

  1. O-M175(xM119,M95,M122) is sometimes incorrectly called "O*".
  2. The outlier Kadai branch is called "Kra" by Thai linguist Weera Ostapirat and "Geyang" by Chinese linguists.

Works cited

Journals

Websites

References

  1. 1.0 1.1 1.2 Shi Yan, Chuan-Chao Wang, Hong-Xiang Zheng et al. (2013), "Y Chromosomes of 40% Chinese Are Descendants of Three Neolithic Super-grandfathers." E-print at arXiv:1310.3897 [q-bio.PE].
  2. Li, Hui; Huang, Ying; Mustavich, Laura F.; Zhang, Fan; Tan, Jing-Ze; Ling-; Wang, E; Qian, Ji; Gao, Meng-He; Jin, Li (2007). "Y chromosomes of prehistoric people along the Yangtze River". Human Genetics 122 (3-4): 383–388. doi:10.1007/s00439-007-0407-2. PMID 17657509.
  3. Cai, X; Qin, Z; Wen, B; Xu, S; Wang, Y et al. (2011). "Human Migration through Bottlenecks from Southeast Asia into East Asia during Last Glacial Maximum Revealed by Y Chromosomes". PLoS ONE 6 (8): e24282. doi:10.1371/journal.pone.0024282. PMC 3164178. PMID 21904623.

External links