HTR3D

5-hydroxytryptamine (serotonin) receptor 3D, ionotropic

Identifiers

HTR3D ; 5HT3D

External IDs

OMIM: 610122 HomoloGene: 52320 IUPHAR: 376 ChEMBL: 4673 GeneCards: HTR3D Gene

Gene ontology
Molecular function	• extracellular ligand-gated ion channel activity
Cellular component	• plasma membrane • integral to membrane
Biological process	• ion transmembrane transport • transmembrane transport
Sources: Amigo / QuickGO

Orthologs

Species

Human

Mouse

n/a

n/a

n/a

RefSeq (mRNA)

NM_001145143

n/a

RefSeq (protein)

NP_001138615

n/a

Location (UCSC)

Chr 3:
183.75 – 183.76 Mb

n/a

PubMed search

n/a

5-hydroxytryptamine receptor 3D is a protein that in humans is encoded by the HTR3D gene.^[1]^[1] The protein encoded by this gene is a subunit of the 5-HT3 receptor.

References

↑ 1.0 1.1 Niesler B, Frank B, Kapeller J, Rappold GA (Jun 2003). "Cloning, physical mapping and expression analysis of the human 5-HT3 serotonin receptor-like genes HTR3C, HTR3D and HTR3E". Gene 310: 101–11. doi:10.1016/S0378-1119(03)00503-1. PMID 12801637.

External links

HTR3D protein, human at the US National Library of Medicine Medical Subject Headings (MeSH)

PDB gallery

Template:PDB Gallery/200909

Ion channel, cell surface receptor: ligand-gated ion channels

Cys-loop receptors

5-HT/serotonin	5-HT₃ A B C D E

GABA	GABA_A α₁ α₂ α₃ α₄ α₅ α₆ β₁ β₂ β₃ γ₁ γ₂ γ₃ δ ε π θ GABA_A-ρ ρ₁ ρ₂ ρ₃

Glycine	α₁ α₂ α₃ α₄ β

Nicotinic acetylcholine	monomers: α1 α2 α3 α4 α5 α6 α7 α9 α10 β1 β2 β3 β4 δ ε pentamers: (α3)₂(β4)₃ (α4)₂(β2)₃ (α7)₅ (α1)₂(β4)₃ - Ganglion type (α1)₂β1δε - Muscle type

Zinc	Zinc-activated

Ionotropic glutamates

Ligand-gated only	AMPA (1 2 3 4) Kainate 1 2 3 4 5

Voltage- and ligand-gated	NMDA 1 2A 2B 2C 2D 3A 3B L1A L1B

‘Orphan’	GluD δ₁ δ₂

ATP-gated channels

Purinergic receptors	P2X 1 2 3 4 5 6 7

Index of signal transduction

Description	Intercellular neuropeptides growth factors cytokines hormones Cell surface receptors ligand-gated enzyme-linked G protein-coupled immunoglobulin superfamily integrins neuropeptide growth factor cytokine Intracellular adaptor proteins GTP-binding MAP kinase Calcium signaling Lipid signaling Pathways hedgehog Wnt TGF beta MAPK ERK notch JAK-STAT apoptosis hippo TLR

HTR3D

References

Further reading

External links