HLA-B73

major histocompatibility complex (human), class I, B73
Alleles B*7301
Structure (See HLA-B)
Symbol(s) HLA-B
EBI-HLA B*7301
Locus chr.6 6p21.31

HLA-B73 (B73) is an HLA-B serotype. The serotype identifies the HLA-B*7301 gene product.[1] Part of B*7301 is similar to the HLA-B22 family, however part resembles the domains seen in other apes.[2] B73 is more common in Western Indian Ocean, Mediterranean and Africa. (For terminology help see: HLA-serotype tutorial)

Serotype

B73 serotype recognition of B*7301 allele-group gene products[3]
B*73 B73 Other Sample
allele % % size (N)
7301 22 69 106

B*7301 frequencies

HLA B*7301 frequencies
freq
ref. Population (%)
[4] Parsi (Karachi, Pakistan) 4.9
[4] United Arab Emirates2.0
[4] Italy2.0
[4] Seri (Sonora, Mexico)1.5
[4] P'urhépecha (Michoacán, Mexico) 1.5
[4] Jews (Israel) (*2 studies)1.2
[4] Beti (Cameroon)1.1
[4] Casablanca (Morocco)0.9
[4] Tbilisi (Georgia)0.9
[4] Mossi (Burkina Faso)0.9
[4] Bulgaria0.9
[4] Sudanese0.8
[4] Tuva (Russia) (2)0.8
[4] Oman0.8
[4] Bamileke (Cameroon)0.6
[4] Pathan (Pakistan)0.5
[4] Khalkha (Mongolia)0.5
[4] Druse Arabs (Israel) 0.5
[4] Baloch (Iran)0.5
[4] Manchester (England)0.5
[4] Algeria (1)0.5
[4] Turkey0.4
[4] Amman (Jordan)0.3
[4] Shona (Harare, Zimbabwe) 0.2
[4] Republic of Macedonia 0.2
[4] Nandi (Kenya)0.2
[4] Luo (Kenya)0.2
[4] Campania (Italy)0.2
[4] Greece0.2

References

  1. ↑ Marsh SG; Albert ED; Bodmer WF et al. (2005). "Nomenclature for factors of the HLA system, 2004". Tissue Antigens 65 (4): 301–69. doi:10.1111/j.1399-0039.2005.00379.x. PMID 15787720.
  2. ↑ Hoffmann HJ, Kristensen TJ, Jensen TG, Graugaard B, Lamm LU (1995). "Antigenic characteristics and cDNA sequences of HLA-B73". Eur. J. Immunogenet. 22 (3): 231–40. doi:10.1111/j.1744-313X.1995.tb00237.x. PMID 8547229.
  3. ↑ derived from IMGT/HLA
  4. ↑ 4.0 4.1 4.2 4.3 4.4 4.5 4.6 4.7 4.8 4.9 4.10 4.11 4.12 4.13 4.14 4.15 4.16 4.17 4.18 4.19 4.20 4.21 4.22 4.23 4.24 4.25 4.26 4.27 4.28 Middleton D, Menchaca L, Rood H, Komerofsky R (2003). "New allele frequency database: http://www.allelefrequencies.net". Tissue Antigens 61 (5): 403–7. doi:10.1034/j.1399-0039.2003.00062.x. PMID 12753660.