HLA-B54

major histocompatibility complex (human), class I, B54
Alleles B*5401
Structure (See HLA-B)
Symbol(s) HLA-B
EBI-HLA B*5401
Locus chr.6 6p21.31

HLA-B54 (B54) is an HLA-B serotype. B54 is a split antigen from the B22 broad antigen, sister serotypes are B55 and B56.[1] The serotype identifies the more common HLA-B*55 gene products.[2]

Serotype

B54 and B22 serotype recognition of HLA B*5401 allele[3]
B*54 B54 B22 Sample
allele % % size (N)
5401 67 3 631

Allele distribution

HLA B*5401 frequencies
freq
ref. Population (%)
[4] USA Hawaii Okinawa10.6
[4] Japan Central7.7
[4] South Korea (3)5.9
[4] China Guangzhou4.5
[4] Thailand (3)4.1
[4] China Inner Mongolia3.4
[4] China North Han3.3
[4] China Beijing Shijiazhuang Tianjian Han3.0
[4] China South Han2.5
[4] Russia Tuva pop 22.2
[4] China Guangxi Maonan1.9
[4] Thailand1.8
[4] Taiwan Thao1.7
[4] China Tibet Autonomous Region Tibetans1.3


See also

References

  1. ↑ Hildebrand WH, Madrigal JA, Little AM, Parham P (1992). "HLA-Bw22: a family of molecules with identity to HLA-B7 in the alpha 1-helix". J. Immunol. 148 (4): 1155–62. PMID 1737933.
  2. ↑ Marsh SG, Albert ED, Bodmer WF et al. (2005). "Nomenclature for factors of the HLA system, 2004". Tissue Antigens 65 (4): 301–69. doi:10.1111/j.1399-0039.2005.00379.x. PMID 15787720.
  3. ↑ derived from IMGT/HLA
  4. ↑ 4.0 4.1 4.2 4.3 4.4 4.5 4.6 4.7 4.8 4.9 4.10 4.11 4.12 4.13 Middleton D, Menchaca L, Rood H, Komerofsky R (2003). "New allele frequency database: http://www.allelefrequencies.net". Tissue Antigens 61 (5): 403–7. doi:10.1034/j.1399-0039.2003.00062.x. PMID 12753660.