Guanosine diphosphate mannose
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Names | ||
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IUPAC name
[(2R,3S,4R,5R)-5-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl (2R,3S,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl dihydrogen diphosphate | ||
Identifiers | ||
3123-67-9 | ||
ChEBI | CHEBI:15820 ![]() | |
ChemSpider | 17372 ![]() | |
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Jmol-3D images | Image | |
MeSH | Guanosine+Diphosphate+Mannose | |
PubChem | 18396 | |
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Properties | ||
C16H25N5O16P2 | ||
Molar mass | 605.341 g/mol | |
Except where noted otherwise, data is given for materials in their standard state (at 25 °C (77 °F), 100 kPa) | ||
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Infobox references | ||
Guanosine diphosphate mannose or GDP-mannose is a nucleotide sugar that is a substrate for glycosyltransferase reactions in metabolism. This compound is a substrate for enzymes called mannosyltransferases.
Biosynthesis
GDP-mannose is produced from GTP and mannose-6-phosphate by the enzyme mannose-1-phosphate guanylyltransferase.[1]
References
- ↑ Samuel G, Reeves P (2003). "Biosynthesis of O-antigens: genes and pathways involved in nucleotide sugar precursor synthesis and O-antigen assembly". Carbohydr. Res. 338 (23): 2503–19. doi:10.1016/j.carres.2003.07.009. PMID 14670712.
See also
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