Guanine deaminase

Guanine deaminase (EC 3.5.4.3, guanase, guanine aminase, GAH, guanine aminohydrolase) is an enzyme which converts guanine to xanthine.^[1]^[2]^[3]

References

↑ Hitchings, G.H. and Falco, E.A. (1944). "The identification of guanine in extracts of Girella nigricans. The specificity of guanase". Proc. Natl. Acad. Sci. USA 30: 294–297. doi:10.1073/pnas.30.10.294. PMC 1078714. PMID 16578130.
↑ Kalckar, H.M. (1947). "Differential spectrophotometry of purine compounds by means of specific enzymes. III. Studies of the enzymes of purine metabolism". J. Biol. Chem. 167: 461–475.
↑ Rabinowitz, J.C. and Barker, H.A. (1956). "Purine fermentation by Clostridium cylindrosporum. II. Purine transformations". J. Biol. Chem. 218 (1): 161–173. PMID 13278325.

Guanine deaminase at the US National Library of Medicine Medical Subject Headings (MeSH)

Hydrolases: carbon-nitrogen non-peptide (EC 3.5)

3.5.99: Other

Anabolism

R5P→IMP:	Ribose-phosphate diphosphokinase Amidophosphoribosyltransferase Phosphoribosylglycinamide formyltransferase AIR synthetase (FGAM cyclase) Phosphoribosylaminoimidazole carboxylase Phosphoribosylaminoimidazolesuccinocarboxamide synthase IMP synthase

IMP→AMP:	Adenylosuccinate synthase Adenylosuccinate lyase reverse AMP deaminase

IMP→GMP:	IMP dehydrogenase GMP synthase reverse GMP reductase

Catabolism

Anabolism

CAD Carbamoyl phosphate synthase II Aspartate carbamoyltransferase Dihydroorotase

Dihydroorotate dehydrogenase Orotidine 5'-phosphate decarboxylase/Uridine monophosphate synthetase

CTP synthetase

Catabolism

Index of inborn errors of metabolism

Description	Metabolism Enzymes and pathways: citric acid cycle enzymes pentose phosphate intermediates glycoproteins enzymes glycosaminoglycans proteoglycan enzymes phospholipid metabolism cholesterol and steroid intermediates sphingolipids enzymes eicosanoids enzymes amino acid intermediates urea cycle enzymes nucleotide intermediates

Disorders	Citric acid cycle and electron transport chain Glycoprotein Proteoglycan Fatty-acid Phospholipid Cholesterol and steroid Eicosanoid Amino acid Purine-pyrimidine Heme metabolism Symptoms and signs

Treatment	Drugs other