Gsx (gene family)

The Gsx gene family are a group of genes found in many, but not all, animals. Gsx genes contain a homeobox DNA sequence and code for proteins that act as transcription factors. The human genome has two Gsx genes, called GSX1 and GSX2 (formerly GSH1 and GSH2), while the fruitfly Drosophila has a single Gsx gene called ind. Vertebrate Gsx genes are implicated in neural patterning.^[1][2] In many animals, Gsx genes can be part of a ParaHox gene cluster.^[3]

References

1. ↑ Cornell RA, Ohlen TV (2000) Curr Op. Neurobiol 10:63-71
2. ↑ Pei, Z; Wang, B; Chen, G; Nagao, M; Nakafuku, M; Campbell, K (Jan 25, 2011). "Homeobox genes Gsx1 and Gsx2 differentially regulate telencephalic progenitor maturation.". Proceedings of the National Academy of Sciences of the United States of America 108 (4): 1675–80. doi:10.1073/pnas.1008824108. PMC 3029701. PMID 21205889. 
3. ↑ Brooke et al 1998 Nature 392: 920-922. doi:10.1038/31933 PMID 9582071