Growth hormone-binding protein
| growth hormone receptor | |
|---|---|
| Identifiers | |
| Symbol | GHR |
| Entrez | 2690 |
| HUGO | 4263 |
| OMIM | 600946 |
| RefSeq | NM_000163 |
| UniProt | P10912 |
| Other data | |
| Locus | Chr. 5 p13-p12 |
Growth hormone-binding protein is a carrier protein for growth hormone.
It is coded by the same gene as growth hormone receptor.
Low levels of Growth Hormone binding protein may indicate a growth hormone receptor problem, and thus a growth hormone insensitivity, rather than a growth hormone deficiency. Normal serum levels of growth hormone Binding Protein 3 may rule out growth hormone insensitivities, like those seen in Laron syndrome.
External links
- somatotropin-binding protein at the US National Library of Medicine Medical Subject Headings (MeSH)
- Baumann, Gerhard; Shaw, Melissa A.; Winter, Robert J. (1987). "Absence of the Plasma Growth Hormone-Binding Protein in Laron-Type Dwarfism". Journal of Clinical Endocrinology & Metabolism 65 (4): 814–6. doi:10.1210/jcem-65-4-814. PMID 3654924.
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