Granuloma faciale

Granuloma faciale
Classification and external resources
ICD-10	L92.2
ICD-9	701.8
DiseasesDB	33779
eMedicine	derm/170

Granuloma faciale (GF) is an uncommon benign chronic skin disease of unknown origin characterized by single or multiple cutaneous nodules, usually occurring over the face.^[1]^:836 Occasionally, extrafacial involvement is noted, most often on sun-exposed areas.

History

GF was first described in 1945 by John Edwin Mackonochie Wigley (1892–1962).^[2]

Differential diagnosis

The disease mimics many other dermatoses and can be confused with conditions, such as sarcoidosis, discoid lupus erythematosus, mycosis fungoides, and fixed drug eruption.

References

↑ James, William D.; Berger, Timothy G.; et al. (2006). Andrews' Diseases of the Skin: clinical Dermatology. Saunders Elsevier. ISBN 0-7216-2921-0.
↑ Wigley, J. E. (1945). "Eosinophilic Granuloma. ? Sarcoid of Boeck". Proceedings of the Royal Society of Medicine 38 (3): 125–126. PMC 2181658. PMID 19992999.

Cutaneous keratosis, ulcer, atrophy, and necrobiosis (L82–L94, 700–701.5)

Epidermal thickening

keratoderma: Keratoderma climactericum
Paraneoplastic keratoderma
- Acrokeratosis paraneoplastica of Bazex
Aquagenic keratoderma
Drug-induced keratoderma
Paraneoplastic keratoderma
psoriasis
- Keratoderma blennorrhagicum

other hyperkeratosis: Acanthosis nigricans
- Confluent and reticulated papillomatosis
Callus
Ichthyosis acquisita
Arsenical keratosis
Chronic scar keratosis
Hyperkeratosis lenticularis perstans
Hydrocarbon keratosis
Hyperkeratosis of the nipple and areola
Inverted follicular keratosis
Lichenoid keratosis
Multiple minute digitate hyperkeratosis
PUVA keratosis
Reactional keratosis
Stucco keratosis
Thermal keratosis
Viral keratosis
Warty dyskeratoma
Waxy keratosis of childhood

Necrobiosis/granuloma

Necrobiotic/palisading	Granuloma annulare Perforating Generalized Subcutaneous Granuloma annulare in HIV disease Localized granuloma annulare Patch-type granuloma annulare Necrobiosis lipoidica Annular elastolytic giant cell granuloma Granuloma multiforme Necrobiotic xanthogranuloma Palisaded neutrophilic and granulomatous dermatitis Rheumatoid nodulosis Interstitial granulomatous dermatitis/Interstitial granulomatous drug reaction

Foreign body granuloma	Beryllium granuloma Mercury granuloma Silica granuloma Silicone granuloma Zirconium granuloma Soot tattoo Tattoo Carbon stain

Other/ungrouped	eosinophilic dermatosis Granuloma faciale

Dermis/
localized CTD

Cutaneous lupus erythematosus	chronic: Discoid Panniculitis subacute: Neonatal ungrouped: Chilblain Lupus erythematosus–lichen planus overlap syndrome Tumid Verrucous Rowell's syndrome

Scleroderma/ Morphea	Localized scleroderma Localized morphea Morphea–lichen sclerosus et atrophicus overlap Generalized morphea Atrophoderma of Pasini and Pierini Pansclerotic morphea Morphea profunda Linear scleroderma

Atrophic/ atrophoderma	Lichen sclerosus Anetoderma Schweninger–Buzzi anetoderma Jadassohn–Pellizzari anetoderma Atrophoderma of Pasini and Pierini Acrodermatitis chronica atrophicans Semicircular lipoatrophy Follicular atrophoderma Linear atrophoderma of Moulin

Perforating	Kyrle disease Reactive perforating collagenosis Elastosis perforans serpiginosa Perforating folliculitis Acquired perforating dermatosis

Skin ulcer	Pyoderma gangrenosum

Other	Calcinosis cutis Sclerodactyly Poikiloderma vasculare atrophicans Ainhum/Pseudo-ainhum

Index of skin

Description	Anatomy Physiology connective tissue Development

Disease	Infections by morphology Vesiculobullous Dermatitis and eczema factitial Papulosquamous Urticaria and erythema Radiation-related Pigmentation Mucinoses Keratosis, ulcer, atrophy, and necrobiosis Vasculitis Fat Neutrophilic and eosinophilic Congenital Neoplasms and cancer nevi and melanomas epidermis dermis Symptoms and signs eponymous Terminology

Treatment	Procedures Drugs antibiotics disinfectants emollients and protectives itch psoriasis other Wound and ulcer

Neutrophilic and eosinophilic dermatoses (L98.2-3)

Eosinophilic dermatosis

With vasculitis	Eosinophilic vasculitis Churg–Strauss syndrome

Without vasculitis	Arthropod assault Eosinophilic cellulitis Hypereosinophilic syndrome Papuloerythroderma of Ofuji Granuloma faciale Eosinophilic folliculitis

Ungrouped	Angiolymphoid hyperplasia with eosinophilia/Kimura's disease Annular erythema of infancy Eosinophilic fasciitis Eosinophilic granuloma Eosinophilic ulcer of the oral mucosa Erythema toxicum neonatorum Incontinentia pigmenti Itchy red bump disease Juvenile xanthogranuloma Pachydermatous eosinophilic dermatitis Papular eruption of blacks Pruritic papular eruption of HIV disease

Reactive neutrophilic dermatoses

Epidermis

Dermis

without vasculitis:	Sweet's syndrome Pyoderma gangrenosum Bowel-associated dermatosis–arthritis syndrome

with vasculitis:	Neutrophilic dermatosis of the dorsal hands

Ungrouped

Index of skin

Description	Anatomy Physiology connective tissue Development

Disease	Infections by morphology Vesiculobullous Dermatitis and eczema factitial Papulosquamous Urticaria and erythema Radiation-related Pigmentation Mucinoses Keratosis, ulcer, atrophy, and necrobiosis Vasculitis Fat Neutrophilic and eosinophilic Congenital Neoplasms and cancer nevi and melanomas epidermis dermis Symptoms and signs eponymous Terminology

Treatment	Procedures Drugs antibiotics disinfectants emollients and protectives itch psoriasis other Wound and ulcer

Index of cells from bone marrow

Description	Immune system Cells Physiology coagulation proteins granule contents colony-stimulating heme and porphyrin metabolism intermediates

Disease	Red blood cell Monocyte and granulocyte Neoplasms and cancer Histiocytosis Symptoms and signs eponymous Blood tests findings

Treatment	Transfusion Drugs thrombosis bleeding other

Granuloma faciale

History

Differential diagnosis

See also

References