Glisoxepide

Glisoxepide
Identifiers


ATC code	A10BB11
CAS Registry Number	25046-79-1^Y
ChEMBL	ChEMBL2106618
ChemSpider	30380^Y
DrugBank	DB01289^Y
InChI InChI=1S/C20H27N5O5S/c1-15-14-18(23-30-15)19(26)21-11-10-16-6-8-17(9-7-16)31(28,29)24-20(27)22-25-12-4-2-3-5-13-25/h6-9,14H,2-5,10-13H2,1H3,(H,21,26)(H2,22,24,27)^Y Key: ZKUDBRCEOBOWLF-UHFFFAOYSA-N^Y InChI=1/C20H27N5O5S/c1-15-14-18(23-30-15)19(26)21-11-10-16-6-8-17(9-7-16)31(28,29)24-20(27)22-25-12-4-2-3-5-13-25/h6-9,14H,2-5,10-13H2,1H3,(H,21,26)(H2,22,24,27) Key: ZKUDBRCEOBOWLF-UHFFFAOYAG
Jmol-3D images	Image
KEGG	D07118^Y
PubChem	32778
SMILES O=C(NCCc1ccc(cc1)S(=O)(=O)NC(=O)NN2CCCCCC2)c3noc(c3)C
UNII	H7SC0I332I^Y
Properties
Chemical formula	C₂₀H₂₇N₅O₅S
Molar mass	449.52388 g/mol
Except where noted otherwise, data is given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
Y verify (what is: Y/N?)
Infobox references

Glisoxepide (INN) is an anti-diabetic drug from the group of sulfonylureas.^[1]

References

↑ Haupt E, Köberich W, Beyer J, Schöffling K (December 1971). "Pharmacodynamic aspects of tolbutamide, glibenclamide, glibornuride and glisoxepide. I. Dose response relations and repeated administration in diabetic subjects". Diabetologia 7 (6): 449–54. doi:10.1007/bf01212061. PMID 5004178.

Oral anti-diabetic drugs and Insulin analogs (A10)

Sensitizers

Biguanides	Metformin^# Buformin^‡ Phenformin^‡

TZDs/"glitazones" (PPAR)	Pioglitazone Rivoglitazone^† Rosiglitazone Troglitazone^‡

Dual PPAR agonists	Aleglitazar^† Muraglitazar^§ Saroglitazar Tesaglitazar^§

Secretagogues

Sulfonylureas	1st generation: Acetohexamide Carbutamide Chlorpropamide Metahexamide Tolbutamide Tolazamide 2nd generation: Glibenclamide (Glyburide)^# Glibornuride Glipizide Gliquidone Glisoxepide Glyclopyramide Glimepiride Gliclazide

Meglitinides/"glinides"	Nateglinide Repaglinide Mitiglinide

Analogs/other insulins

Other

Alpha-glucosidase inhibitors	Acarbose Miglitol Voglibose

Amylin analog	Pramlintide

SGLT2 inhibitors	Canagliflozin Dapagliflozin Empagliflozin^† Remogliflozin^§ Sergliflozin^§ Tofogliflozin^†

Other	Bromocriptine Benfluorex^‡ Tolrestat^‡

Index of hormones

Description	Glands Hormones thyroid intermediates metabolism mineralocorticoids Physiology Development

Disease	Diabetes Congenital Neoplasms and cancer Other Symptoms and signs eponymous

Treatment	Procedures Drugs calcium balance corticosteroids oral hypoglycemics pituitary and hypothalamic thyroid